Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Examining psychometric properties of the Sinhala version of the 'Opening Minds Scale for Health Care Providers' to measure stigma towards mental illness using confirmatory factor analysis. [PDF]
Samaranayake A +3 more
europepmc +1 more source
Neurotransmitters and the Behavior of Individual Investors: Exploratory and Confirmatory Factor Analysis [PDF]
Mohammad Nazaripour, Babak Zakizadeh
openalex +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Development and validation of the socially shared regulated learning questionnaire: insights from a second-order confirmatory factor analysis. [PDF]
Yang Y, He Z, Wei Y, Tang E.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Development of a brief form of the Chinese version of the Odor Awareness Scale(OAS-B): A confirmatory factor analysis approach to item reduction. [PDF]
Zhang B +8 more
europepmc +1 more source

