Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Confirmatory Factor Analysis Supports the Two-Factor Structure of the Arabic Fear-Avoidance Belief Questionnaire in Patients with Low Back Pain. [PDF]
Alnahdi AH, Aldaihan MM, Alsubiheen AM.
europepmc +1 more source
Employers' Perception and Practice of Workplace Violence Prevention at Healthcare Facilities Questionnaire: A Confirmatory Factor Analysis. [PDF]
Mohamad Yazid MN+5 more
europepmc +1 more source
Assessing suicide risk among callers to crisis hotlines: A confirmatory factor analysis [PDF]
Tracy K. Witte+5 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Psychometric properties of the Swedish version of the Patient Health Questionnaire-9: an investigation using Rasch analysis and confirmatory factor analysis. [PDF]
Forsström D+14 more
europepmc +1 more source
A Confirmatory Factor Analysis of the 'Return to Duty Readiness Questionnaire'. [PDF]
Cooper C, Frey B, Long H, Day C.
europepmc +1 more source
Confirmatory factor analysis of the occupational stress inventory-revised among Australian teachers [PDF]
Bahr, Mark+2 more
core
Confirmatory factor analysis and recommendations for improvement of the Autonomy‐Preference‐Index (API) [PDF]
Daniela Simón+6 more
openalex +1 more source