Results 71 to 80 of about 7,733,807 (307)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Discouraging ROK Development of Nuclear Weapons [PDF]

open access: yes, 2013
FY 2013-2014. Project Lead: Bruce BennettIronically, the greatest likelihood for nuclear proliferation in the coming years may come from U.S. allies. The development of nuclear weapons by South Korea (ROK) could result in a regional nuclear arms race and
Center on Contemporary Conflict
core  

Response-efficacy messages produce stronger passwords than self-efficacy messages … for now: A longitudinal experimental study of the efficacy of coping message types on password creation behaviour

open access: yesComputers in Human Behavior Reports
User non-adherence to password guidelines remains a persistent challenge in the fight against cyberattacks. Many users circumvent password requirements by choosing weak, easy-to-guess passwords. This study tests the effectiveness of coping messages (i.e.,
Joelle Simon   +2 more
doaj   +1 more source

Local Conflict Coloring [PDF]

open access: yes, 2016
Locally finding a solution to symmetry-breaking tasks such as vertex-coloring, edge-coloring, maximal matching, maximal independent set, etc., is a long-standing challenge in distributed network computing. More recently, it has also become a challenge in
Fraigniaud, Pierre   +2 more
core   +4 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

A functional dissociation of conflict processing within anterior cingulate cortex [PDF]

open access: yes, 2008
Goal-directed behavior requires cognitive control to regulate neural processing when conflict is encountered. The dorsal anterior cingulate cortex (dACC) has been associated with detecting response conflict during conflict tasks. However, recent findings
Chobok Kim, James Kroger, Jeounghoon Kim
core   +1 more source

The role of the Russian Federation in the Pridnestrovian conflict: an international humanitarian law perspective [PDF]

open access: yes, 2008
Pridnestrovie, a de facto state within the territory of the Republic of Moldova, declared itself independent in September 1990, a declaration that was followed by an armed conflict between Moldova and Pridnestrovie in 1992. To date no settlement has been
Higgins, Noelle, O'Reilly, Kieran
core   +2 more sources

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

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