Results 241 to 250 of about 4,219,171 (314)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Conflict Behaviour Frequency During Show Jumping Competitions: A Practical Study. [PDF]

Animals (Basel)
Nothaft IT, Padilha FGF, Meriade GB, Leite JDS, Ferreira AMR.   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Health literacy as a mediator between work-family conflict and anxiety and depressive symptoms among white- and blue-collar workers in China. [PDF]

Front Public Health
Yuan J, Luo L.
europepmc   +1 more source

Work-Family Conflict and Intention to Leave Among Nursing Professionals: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Ventura-Silva JMA, Ribeiro OMPL, Ribeiro MP, Faria ADCA, Barros SCDC, Gasparino RC, Silva CB, Forte ECN, Bozzetti M, Demirsoy N, Zuge SS.   +10 more
europepmc   +1 more source

Concatenation, Conflict, and Complexity: Genealogical Heterogeneity Mimics Substitutional Heterogeneity for Nucleotide Model Selection. [PDF]

J Mol Evol
Lozano JR, Miya MS, Turner E, McKenna D, Adams R.   +4 more
europepmc   +1 more source

Tuberculosis and tuberculosis-human immunodeficiency virus in post-conflict West Africa: Lessons for integrated surveillance from 2000 to 2022. [PDF]

J Public Health Afr
Duah JK.
europepmc   +1 more source

Divorce conflict and health across the divorce process: A 10-year observational study of medicine prescriptions, primary care visits and hospitalisations. [PDF]

Br J Health Psychol
Hald AN, Hald GM, Fallesen P.
europepmc   +1 more source