Results 61 to 70 of about 150,034 (233)
Legal and Moral Justifications of the Israeli Military Against the Axis of Resistance: A Just War Theory Perspective [PDF]
پژوهشنامه حقوق اسلامی∴ Introduction ∴ In the contemporary international landscape, the ethical nature of warfare remains a pivotal concern for global leaders seeking to justify military actions to their constituencies and the wider world.
Ali Karimy, Mohammad Hosein Safaei
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Interprofessional conflict between doctors and nurses remains a persistent challenge in healthcare systems globally, especially in resource-constrained settings like Nigeria. In Kogi State, systemic issues such as poor infrastructure, inadequate staffing, and role ambiguity have intensified doctor–nurse tensions, with adverse consequences for patient ...
Yunusa, Edime +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Redefining Global Physicians in Response to Turkey’s Violation of Medical Neutrality
Voices in Bioethics, 2014 This paper discusses the global role of doctors in light of a new piece of legislation passed by Turkey on January 17, 2014 that criminalizes emergency medical care outside of hospitals.
Kate Zavin
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Antimicrobial Resistance and Infection ControlBackground Strengthening infection prevention and control (IPC) is crucial for mitigating the risks of infections and antimicrobial resistance in healthcare facilities. The conflict in Tigray has had serious repercussions on the health system. This study
Akeza Awealom Asgedom +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source