Results 111 to 120 of about 10,675,536 (259)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Environmental conflict and decision-making: the case of hydroelectric power

, 2012
As management of the environment becomes more complex and the number of potentially conflicting issues to be balanced expands, there will be increasing and more intense debates about the course(s) of action(s) to be taken.
Watkin, L, Watkin, L.
core   +1 more source

Bedouin Adolescents during the Iron Swords War: What Strategies Help Them to Cope Successfully with the Stressful Situation?

Behavioral Sciences
This study examined the emotional reactions and coping resources of Bedouin teenagers (ages 12–18) following the events of 7 October 2023 and the subsequent Iron Swords War between Israel and Hamas forces in Gaza.
Haled Al-Said, Orna Braun-Lewensohn
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Building CEWARN around Intra-state Conflict Management: Theory and Practice

, 2002
The Horn of Africa has come to be defined by the frequency and intensity of its violent conflicts. Yet, whereas in other regions conflict prevention stresses formal, top-down inter-governmental structures, in the Horn of Africa an alternative conflict ...
Adelman, Howard
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Conflict management in organizations

У дослідженні схарактеризовано поняття «конфлікт». Висвітлено умови вдосконалення. Упорядковано засоби діагностики досліджуваної проблеми. Відповідно до структури комплексно-цільової програми визначено систему заходів забезпечення конструктивного ...
Рябоконь, Д. М.
core  

The effects of OCB on work group conflict [PDF]

, 2007
vi, 52 leaves ; 29 cm. --This study examined how Organizational Citizenship Behavior (OCB) climate affected levels of task and relationship conflict within work groups. Moderating effects were provided by the attributions the participants gave to the OCB
University of Lethbridge. Faculty of Management, Pyne, Tom   +1 more
core  

A Network-based framework for strategic conflict resolution [PDF]

, 2009
Strategic conflict in this work refers to the spectrum of co-operative and oppositional activities in which organisations engage when their interests meet.
Powell, J. H.
core   +1 more source