Results 81 to 90 of about 10,675,536 (259)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Konserniyhtiön maksukyvyttömyys ja konkurssi [PDF]

open access: yes, 2013
Verkkoversio: Helsingin yliopisto, 2022Konkurssioikeuden tutkimus on perinteisesti keskittynyt yritysten konkursseihin. Siinäkin se on yksinkertaistanut monimuotoista todellisuutta: tutkimuskohteeksi on valittu tai valikoitunut erillisen, itsenäisesti ...
Koulu, Risto
core   +1 more source

THE REPRISAL ATTACKS BY AL-SHABAAB AGAINST KENYA [PDF]

open access: yesJournal of Defense Resources Management, 2013
The incursion of Kenya Defence Forces (KDF) into Somalia was met by a series of threats from the Al-Shabaab that it would increase the attacks against Kenya if the troops were not withdrawn.
E.O.S.ODHIAMBO   +5 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

GREEN FINANCE AS A CATALYST FOR TECHNOLOGICAL INNOVATION: A HETEROGENEOUS ANALYSIS OF EMERGING ECONOMIES

open access: yesEconomic Review
The role of green finance in driving technological innovation in resource-constrained emerging economies is examined. Despite substantial inflows, many nations struggle to convert funds into green technology advancements, prompting questions about ...
Saqib Munir, Khawaja Zeeshan Waheed
doaj   +2 more sources

Do leaders walk the extra mile? The contribution of personal and work-related factors on daily step count increase in a university team step challenge

open access: yesFrontiers in Public Health
BackgroundSedentary work environments contribute to low physical activity (PA) levels, which are associated with adverse health and productivity outcomes.
Helena Manger   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Conflict Management

open access: yesJournal of Associated Medical Sciences, 2015
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Prasit Chanarat   +1 more
doaj  

Perceived Economic Gains and the Perpetuation of Female Genital Mutilation in Osun State Nigeria

open access: yesABUAD Journal of the Humanities-AGIDIGBO
The prevalence of Female Genital Mutilation (FGM) in Nigeria is alarming. In Osun State, the prevalence of FGM is 45.9%%, making it one of the highest in Nigeria. This paper examines the prevalence from the perspective of the perceived economic, social,
Oluwayomi Nimat YUSUF   +1 more
doaj   +1 more source

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