RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
This paper investigates the use and potential role of satellite remote sensing (RS) data in documenting conflict incidents and related human rights violations.
Raphaela Edler +3 more
doaj +1 more source
Domain-general conflict monitoring predicts neural and behavioral indices of linguistic error processing during reading comprehension. [PDF]
Brothers T +4 more
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Anodal tDCS modulates specific processing codes during conflict monitoring associated with superior and middle frontal cortices. [PDF]
Adelhöfer N, Stock AK, Beste C.
europepmc +1 more source
The Value Relevance of Forced Top Management Departures [PDF]
This paper studies the value relevance of management turnover based on a sample of Dutch events. Consistent with previous studies we find weak or insignificant aggregate announcement effects on stock prices.
C. Mirjam van Praag, Kees Cools
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The logic of the violence in the civil war: the armed conflict in Colombia [PDF]
This paper proposes a reading of the armed conflict from an evolutionary design that takes into account the Logic of Violence in the Civil War. Their aim is to assess the dynamics of conflict and changes from its author's scientific output.
Estrada, Fernando
core +1 more source
Kapasitas Dan Strategi Kelembagaan Pemerintah Dalam Pengelolaan Konflik Antar Pengguna Sumberdaya Perairan Kabupaten Tanah Laut (Capacity and Strategy of Government's Institution on Conflict Management Between Territorial Resource Waters User) [PDF]
Enactment of Law No. 32 of 2004 on Regional Government, to provide flexibility in managing resources territorial waters. The biggest challenge in the district of South Kalimantan is a conflict between water users.
Apriansyah, A. (Apriansyah) +2 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

