Results 61 to 70 of about 1,692,266 (299)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

The Gratton effect remains after controlling for contingencies and stimulus repetitions.

Frontiers in Psychology, 2014
The Gratton effect, the observation that the size of the Stroop effect is smaller following an incongruent trial compared to a congruent trial, is one pivotal observation in support of the conflict-monitoring hypothesis.
Chris eBlais, Aikaterini eStefanidi, Gene A Brewer   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Context-specific proportion congruency effects: An episodic learning account and computational model

Frontiers in Psychology, 2016
In the Stroop task, participants identify the print colour of colour words. The congruency effect is the observation that response times and errors are increased when the word and colour are incongruent (e.g., the word red in green ink) relative to when ...
James R Schmidt
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Extended Fronto-Striatal Model of Obsessive Compulsive Disorder: Convergence from Event-Related Potentials, Neuropsychology and Neuroimaging

Frontiers in Human Neuroscience, 2012
In this work, we explored convergent evidence supporting the fronto-striatal model of obsessive-compulsive disorder (FSMOCD) and the contribution of event-related potential (ERP) studies to this model.
Margherita eMelloni, Claudia eUrbistondo, Lucas eSedeño, Carlos eGelormini, Rafael eKichic, Agustin eIbanez   +5 more
doaj   +1 more source

Response Conflict and Frontocingulate Dysfunction in Unmedicated Participants with Major Depression [PDF]

, 2010
Individuals with major depressive disorder (MDD) often exhibit impaired executive function, particularly in experimental tasks that involve response conflict and require adaptive behavioral adjustments.
Holmes, Avram, Pizzagalli, Diego
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Detecting self-produced speech errors before and after articulation: An ERP investigation

Frontiers in Human Neuroscience, 2013
It has been argued that speech production errors are monitored by the same neural system involved in monitoring other types of action errors. Behavioral evidence has shown that speech errors can be detected and corrected prior to articulation, yet the ...
Kevin Michael Trewartha, Natalie ePhillips   +1 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source