Results 111 to 120 of about 5,853,531 (371)

Conflict of Interest: Full Transparency

open access: yesArthroplasty Today, 2022
Gregory J. Golladay, MD   +1 more
doaj   +1 more source

Conflicto de intereses Conflict of interest

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2007
La condición humana, en particular el narcisismo normal del adulto, favorece que clínicos, investigadores, miembros de comités de investigación, de asesores y de bioética, así como pares, editores y los industriales del sector de la salud, sean proclives
Santiago Barrios-Vásquez
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Labor Relations Conflict in the Workplace: Scale Development, Consequences and Solutions [PDF]

open access: yes, 2017
Because the goals of employers and employees are often incompatible, conflicts are inevitable and an essential part of organizational life. The three studies reported in this paper addressed the issues of identifying the dimensions of workplace conflicts
Xi, Meng   +3 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

On the origins of a Conflict of Interest in the Mutual Fund Industry [PDF]

open access: yes
Cet article traite des conflits d'intérêts existant entre les investisseurs et leur conseiller financier. Des contributions antérieures ont apporté des éclairages sur cette question en considérant soit les montants investis soit l'horizon d ...
Sébastien M. Lemeunier
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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