Results 81 to 90 of about 5,853,531 (371)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Seed Biofortification and Phytic Acid Reduction: A Conflict of Interest for the Plant?

open access: yesPlants, 2015
Most of the phosphorus in seeds is accumulated in the form of phytic acid (myo-inositol-1,2,3,4,5,6-hexakisphosphate, InsP6). This molecule is a strong chelator of cations important for nutrition, such as iron, zinc, magnesium, and calcium.
F. Sparvoli, E. Cominelli
semanticscholar   +1 more source

Knowing the Soviet Union: the historical dimension [PDF]

open access: yes, 1989
This repository item contains a single article of the Publication Series, papers in areas of particular scholarly interest published from 1989 to 1996 by the Boston University Institute for the Study of Conflict, Ideology, and Policy.
Conquest, Robert
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Professional Responsibility and Conflict of Interest [PDF]

open access: yesStudia Gilsoniana, 2017
When conflicts of interests arise for the professional, s/he should be aided in their resolution by a long-standing body of knowledge called ethics. Ethics provides an array of concepts, vocabulary, and strategies to aid in both the understanding and the
Lois Eveleth
doaj  

Conflict of interest and signal interference lead to the breakdown of honest signaling

open access: yesEvolution; international journal of organic evolution, 2015
Animals use signals to coordinate a wide range of behaviors, from feeding offspring to predator avoidance. This poses an evolutionary problem, because individuals could potentially signal dishonestly to coerce others into behaving in ways that benefit ...

semanticscholar   +1 more source

Introduction: The public health crisis in communist systems [PDF]

open access: yes, 1990
This repository item contains a single article of the Publication Series, papers in areas of particular scholarly interest published from 1989 to 1996 by the Boston University Institute for the Study of Conflict, Ideology, and Policy.
Armes, Keith
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

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