Results 111 to 120 of about 725,674 (302)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Briefing Note: Human Rights and Conflict Transformation [PDF]

open access: yes, 2017
This briefing note seeks to provide a summary of key arguments relating to the link between human rights, prevention and conflict transformation (including conflict recurrence and post-conflict criminal violence, ie transmutation and transformation of ...
Parlevliet, M.
core  

Working Paper 2-3: Articles addressing current topics related to the EU from a whole of society perspective

open access: yes, 2016
This Working Paper 2-3 is a compilation of several short articles published as part of the project “Whole-of-Society Conflict Prevention and Peacebuilding”, which aims to enhance the EU’s peacebuilding and conflict prevention capabilities.
Urrutia, Pamela   +12 more
core   +1 more source

Conflict Prevention and Resolution: Key Approaches

open access: yesBusiness & Management Compass
This article presents a short literature review and classification of key approaches to conflict prevention and resolution. The great number of conflict management theories, concepts, and methods is often difficult to exploit and because of that, they ...
Petya Angelova
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Information management and communication technology for conflict prevention and peace

open access: yes, 2008
Information management and technology (ICT) has much to offer to support public safety and policing in conflict prevention and peace. Police and public safety agencies have been using ICTs for several decades for managing the processes of investigation ...
Soar, Jeffrey
core  

Maintaining Harmonization In Preventing Potential Social-Religious Conflicts In The City of Semarang Through Community Pluralism Education

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
One of the challenges and threats for religious communities today is the existence of religious fundamentalists who are trying to replace the Pancasila ideology. Apart from that, the diverse lives of the people of Semarang City intersect with differences
Sri Suneki   +2 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Formation of the culture of the inter-ethnic relations of the school yourth in poly-ethnic regions

open access: yesНаука. Культура. Общество, 2019
The article investigates the process of formation of culture of interethnic communication of school youth in multiethnic regions by the results of large-scale longitudinal studies conducted from 1991 to the present time in Astrakhan, Grozny, Ivanovo ...
Larissa S. Ruban
doaj  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy