Results 31 to 40 of about 725,674 (302)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Gender in EU Conflict Prevention and Peacebuilding Policy and Practice
, 2016 This scoping study was produced as part of the project “Whole of Society Conflict Prevention and Peacebuilding”, which aims to enhance the EU’s peacebuilding and conflict prevention capabilities.
Urrutia, Pamela +6 more
core +1 more source
(In)effective planning capacity of CSDP missions: Comparative analysis of EULEX Kosovo and EUFOR Althea [PDF]
Journal of Regional Security, 2017 This paper evaluates the planning capacity of two Common Security and Defence (CSDP) missions (EULEX Kosovo and EUFOR Althea) in order to assess the effectiveness of CSDP planning process.
Boštjancic-Pulko Ivana
doaj
Forging Consensus for Atrocity Prevention: Assessing the Record of the OSCE
Genocide Studies and Prevention: An International Journal, 2018 This essay examines the record of the Organization for Security and Cooperation in Europe (OSCE) in fostering norms and collaborative practices for preventing mass atrocities in Eurasia.
Matthew Levinger
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Conflict Prevention in Estonia: The Role of the Electoral System [PDF]
, 2002 Estonia's success in averting a potential conflict over its Russian-speaking minority is often attributed to the intervention of the OSCE High Commissioner on National Minorities.
Khrychikov, Sergey +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source