Results 41 to 50 of about 725,674 (302)

Uses of Information and Communication Technologies (ICTs) for EU Conflict Prevention and Peacebuilding

open access: yes, 2016
This scoping study was produced as part of the project “Whole of Society Conflict Prevention and Peacebuilding”, which aims to enhance the EU’s peacebuilding and conflict prevention capabilities.
Jennifer Rhian Gaskell   +9 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Participation of the SCO in Peacekeeping Activities, Prevention and Settlement of Conflicts

open access: yesVestnik MGIMO-Universiteta, 2015
: Shanghai Cooperation Oprganization is a multi-functional interstate regional organizaton. One of the main priorities in the activities of the SCO is a cooperation in providing regional security and stability in the areas of counteraction against ...
Kirill M. Barskiy
doaj   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Local Ownership Challenges in Peacebuilding and Conflict Prevention

open access: yes, 2016
This report was produced as part of the project “Whole of Society Conflict Prevention and Peacebuilding”. It analyses local ownership in terms of the EU’s ability to leverage the density and complexity of local society and build positive social capital ...
Martin, Mary   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Replication data for: Assessing the EU's conflict prevention and peacebuilding interventions in Georgia

open access: yes, 2017
The Case Study Report on Georgia was produced as part of the project “Whole-of-Society Conflict Prevention and Peacebuilding” (WOSCAP). It contains the research findings on the EU’s interventions in conflict prevention and peacebuilding in Georgia.
Macharashvili, Nana   +5 more
core   +1 more source

New Paths and Policies Towards Conflict Prevention: Chinese and Swiss Perspectives

open access: yes, 2021
This book explores the discourse on conflict prevention and peacebuilding by bringing together researchers from China and Switzerland over a series policy dialogues.
Tower, Jason G.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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