Results 81 to 90 of about 725,674 (302)

Leadership and Mediation Approaches for Social Cohesion in the Greek Public Sector

open access: yesAdministrative Sciences
This study investigates how inclusive leadership, mentorship, and digital tools shape conflict prevention and social cohesion within the Greek public sector.
Kyriaki Aravidou   +2 more
doaj   +1 more source

The High Commissioner on National Minorities at 20 - Introduction [PDF]

open access: yesJournal on Ethnopolitics and Minority Issues in Europe, 2013
In this JEMIE issue the writings of well-known analysts and observers of the HCNM address questions that span from mandate and its origins to the effectiveness of the institution and its work, pointing also to specific aspects that give added-value to ...
Ilze Brands Kehris
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Whose peace? Why context and local voices matter in reimagining peace education

open access: yesFrontiers in Political Science
This conceptual analysis examines the fluidity of peace as both an idea and a practice, and the shifting positionalities of those who teach and study it.
Dilara Özel
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Conflict Prevention Between Immigrants And Local Community In Bogor, West Java

open access: yesMimbar, 2019
This research examines the conflict prevention between immigrants and the local community in Cisarua, West Java. This research uses a qualitative method with a descriptive approach supported by secondary data.
Bambang Wahyudi, May May Maysarah
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

РЕГИОНАЛНАТА СОРАБОТКА КАКО ФАКТОР ЗА ПРЕВЕНЦИЈА НА КОНФЛИКТИ ВО ЗАПАДЕН БАЛКАН [PDF]

open access: yesBezbednosni Dijalozi, 2010
What is the influence of regional cooperation on conflict prevention in WesternBalkan? The article gives an answer to this main question, starting from the hypothesisthat cooperation between the countries has positive influence on conflict prevention ...
Александар ПАВЛЕСКИ
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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