Results 41 to 50 of about 1,282,606 (297)
Conflict-Probability-Estimation-Based Overtaking for Intelligent Vehicles
IEEE Transactions on Intelligent Transportation Systems, 2009 Overtaking is a complex and hazardous driving maneuver for intelligent vehicles. When to initiate overtaking and how to complete overtaking are critical issues for an overtaking intelligent vehicle. We propose an overtaking control method based on the estimation of the conflict probability.
Fenghui Wang +2 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A New Evidence Weight Combination and Probability Allocation Method in Multi-Sensor Data Fusion
Sensors, 2023 A single sensor is prone to decline recognition accuracy in the face of a complex environment, while the existing multi-sensor evidence theory fusion methods do not comprehensively consider the impact of evidence conflict and fuzziness.
Li Ma +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Quantum Annealing Applied to De-Conflicting Optimal Trajectories for Air Traffic Management [PDF]
, 2018 We present the mapping of a class of simplified air traffic management (ATM) problems (strategic conflict resolution) to quadratic unconstrained boolean optimization (QUBO) problems.
Biswas, Rupak +8 more
core +2 more sources
Second Order Probabilities for Uncertain and Conflicting Evidence
CoRR, 2013 In this paper the elicitation of probabilities from human experts is considered as a measurement process, which may be disturbed by random 'measurement noise'. Using Bayesian concepts a second order probability distribution is derived reflecting the uncertainty of the input probabilities.
openaire +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Complexity Review of NIMBY Conflict: Characteristics, Mechanism and Evolution Simulation
Systems, 2023 In the process of modernization and urbanization, some government projects or facilities with negative externalities have caused the psychology of residents nearby to “Not in My Backyard” (NIMBY).
Luxin Cui, Yu Chen, Xing Wang, Shiyu Liu
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source