Results 111 to 120 of about 5,272,632 (310)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Rwanda, Burundi, and Their Ethnic Conflicts [PDF]
This paper demonstrably dispels the assumption that ethnic conflict in Rwanda and Burundi is a chronic endemic phenomenon. It emphasizes the consolidation of the caste system during the colonial era, intra regional disparities within the two communities,
Isabirye, Stephen B. +1 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Economics of Conflicts of Interest in Financial Institutions [PDF]
A conflict of interest exists when a party to a transaction could potentially make a gain from taking actions that are detrimental to the other party in the transaction. This paper examines the economics of conflicts of interest in financial institutions
Hamid Mehran, Rene M. Stulz
core
The language of certain conflicts of a nondeterministic process [PDF]
The language of certain conflicts is the most general set of behaviours of a nondeterministic process, which certainly lead to a livelock or deadlock when accepted by another process running in parallel.
Malik, Robi
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Race and Christian Interpersonal Relationships [PDF]
Unfortunately no one seems to have a workable and effective plan to resolve societal racial tension that continues to exist in America and in the rest of the world. However, the Bible gives clear instructions as how to resolve racial conflicts.
Brown, Caleb H A
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source

