Results 41 to 50 of about 552,801 (329)
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
A Decidable Confluence Test for Cognitive Models in ACT-R
Computational cognitive modeling investigates human cognition by building detailed computational models for cognitive processes. Adaptive Control of Thought - Rational (ACT-R) is a rule-based cognitive architecture that offers a widely employed framework
D Gall +6 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Overview of Nigeria’s Infrastructural Development
This paper offers a comprehensive analysis of Nigeria’s infrastructural development from 2014 to 2023, focusing on significant achievements and recurring challenges.
Muhammad Onoruiza Audu +1 more
doaj +1 more source
Interactions between groundwater and surface water at river banks and the confluence of rivers [PDF]
Riparian vegetation depends on hydrological resources and has to adapt to changes in water levels and soil moisture conditions. The origin and mixing of water in the streamside corridor were studied in detail.
Fraser +25 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Despite advancements in predictive modeling, existing methods struggle with accuracy and spatial variability in Land Surface Temperature (LST) estimation.
Momohjimoh Abdulsalami +9 more
doaj +1 more source
Seldom does criticism address cross-cultural issues in terms of confluence. In fact, scholars tend to use chaos theory (Glissant, Benitez-Rojo), oceanic tropes (Gilroy, Brathwaite), and linguistic foci (Chamoiseau, Bhabha) to deal with them.
Léo Courbot
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Exploration of quality groundwater through lineament delineation in Okene and its surroudings
This research addresses the issue of unproductive boreholes in the study area and the limited information on productive aquifers. The challenging geological terrain and dense urbanization necessitate the use of integrated airborne data, namely Landsat ...
Oluwatoyin Khadijat Olomo +2 more
doaj +1 more source

