Results 161 to 170 of about 27,035 (253)

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Mechanism of action of soybean oil in arthropods: mortality results from tracheal infiltration and obstruction of gas exchange structures. [PDF]

J Econ Entomol
Castro-Torres R, Valdez-Carrasco J, Rodríguez-Leyva E, Soto-Rojas L, Lomeli-Flores JR.   +4 more
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Teliosporogenesis of the Peanut Smut Fungus <i>Thecaphora frezzii</i> in <i>Arachis hypogaea</i>: A Correlative Multiscale Microscopy Study. [PDF]

Plants (Basel)
Romero MF, Popoff OF, Seijo GJ, Gonzalez AM.   +3 more
europepmc   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Preparation of cleared whole-mount urethra and urinary bladder from transcardially perfused mice for immunolabeling and analysis by CLSM. [PDF]

STAR Protoc
Pfeil U, Dettler F, Perniss A, Anekal PV, Bankova L, Montero LIopis P, Deckmann K.   +6 more
europepmc   +1 more source

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

Advanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen, Lingwei Xue, Gaojie Li, Xueli Chen, Yongjun Han, Liwei Mi, Yuqing Chen   +6 more
wiley   +1 more source

Evaluating the efficacy of Vibrospiral novel sealer placing instrument: a Confocal and Scanning Electron Microscope in-vitro study. [PDF]

BMC Oral Health
Banerjee A, Harikrishna N, Hegde NN, Lakshmi V C, Hegde MN.   +4 more
europepmc   +1 more source

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

Advanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu, Ke Liu, Haotian Liu, Chaoqi He, Xiaozhen Liu, Xin Zeng, Misha Mao, Yuxiao Mu, Ying Li, Qinghui Zheng, Hongchao Tang, Da Qian, Xuli Meng   +12 more
wiley   +1 more source

Comparative Efficacy of Sonic, Ultrasonic, and Diode Laser-Activated Irrigation with Combination of NaOCl/EDTA/CHX Solutions Against <i>Fusobacterium nucleatum</i> in Dentinal Tubules: A Confocal Microscopy Study. [PDF]

Clin Cosmet Investig Dent
Nagadi E, Aripin D, Prisinda D, Primathena I, Ayuningtyas FD, Feronytha AG.   +5 more
europepmc   +1 more source