Results 181 to 190 of about 2,617,420 (275)

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Synergistic growth, metabolic products, and matrix quantification in dual-species biofilms of oral pathogens. [PDF]

J Appl Oral Sci
Velásquez-Espedilla EG, Pedrinha VF, Cuellar MRC, Rosim PLB, Méndez DAC, Cruvinel T, Andrade FB.   +6 more
europepmc   +1 more source

Hydrogel Phase Transition‐Driven Soft Gating Circumvents Debye Screening for Advanced Biosensing

Advanced Science, EarlyView.
A 3D soft gate utilizes a macroscopic hydrogel phase transition to effectively circumvent Debye screening in high‐salt environments. The intact matrix maximizes transmembrane ion flux via volumetric Donnan enrichment and superhydrophilicity. Target‐triggered network disassembly abolishes these effects, introducing a synergistic physical barrier.
Liu Shi, Zimeng Zhang, Bingheng Li, Yalei Gao, Ruirui Zhang, Zheying Mu, Jian Ni, Bing Bo, Genxi Li   +8 more
wiley   +1 more source

Correction: Plastisphere-isolated <i>Stutzerimonas balearica</i> SP-H sustains stable sulfur-autotrophic denitrification under microplastic stress. [PDF]

Front Microbiol
Liu S, Yu Z, Pang J, Xu X, Fang Y, Xing M, Yan J, Ouyang D, Luo Y, Zhang H.   +9 more
europepmc   +1 more source

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source

Influence of Radiotherapy Timing on Sealer-Dentin Adhesion: A Confocal Microscopy and Push-Out Bond Strength Study. [PDF]

J Adhes Dent
Nalci Calik G, Oglakci Ozkoc B, Deger C, Capkin H, Akdur K, Mayadagli A.   +5 more
europepmc   +1 more source

2D Vermiculite Nanosheets Encapsulated in Hydrogel Electrolyte for Shuttle‐Free and Dendrite‐Inhibited Zinc‐Iodine Batteries

Advanced Science, EarlyView.
A dual‐network hydrogel was prepared via a one‐pot method, incorporating vermiculite nanosheets as an additive. The negatively charged vermiculite nanosheets not only coordinate with zinc ions to facilitate Zn plating/stripping and suppress Zn dendrite growth, but also adsorb polyiodides to inhibit the shuttle effect, which significantly improves the ...
Yunlong Zhou, Chuanliang Wei, Huanyu Yang, Bin Li, Bo Yang, Jie Ren, Cheng Ye, Maofeng Zhang   +7 more
wiley   +1 more source

Effects of Acidic Exposure on Surface Properties and Bacterial Adhesion of Three Resin-Based CAD/CAM Materials. [PDF]

Polymers (Basel)
Almuhayya S, Babaier R, Säilynoja E, Somily AM.   +3 more
europepmc   +1 more source

Self‐Adaptive Biomimetic Nanocomposite Hydrogel Orchestrates Dual‐Targeting and On‐Demand H2S Gasotransmission for Multifactorial Diabetic Wound Therapy

Advanced Science, EarlyView.
A self‐adaptive and biomimetic nanocomposite hydrogel is engineered to orchestrate dual‐targeting and on‐demand H2S gasotransmission for multifactorial diabetic wound therapy. By seamlessly integrating antibacterial, antioxidant, anti‐inflammatory, immunoregulatory, and pro‐angiogenic functions within a single platform, this hydrogel dynamically ...
Kefan Wu, Xiaoxue Yang, Yonghang Liu, Yi Xiao, Shiyu Meng, Ao Li, Yi Zhun Zhu, Hui Guo, Xiaolin Wang   +8 more
wiley   +1 more source

Perfluoroether Peptide-Modified Artificial Viral Capsid for Enhanced Doxorubicin Delivery to Liver Cancer Cells. [PDF]

ACS Omega
Ghosh A, Yamamoto Y, Wada M, Takaki Y, Inaba H, Aikawa K, Ota Y, Hirata Y, Okazoe T, Matsuura K.   +9 more
europepmc   +1 more source