Results 191 to 200 of about 44,660 (298)

Evaluating the Effects of Various Antioxidants on Dentinal Tubule Penetrability of a Resin-Based Sealer: A Confocal Laser Microscopic Study. [PDF]

Cureus
Srivastava S, Sinha S, Singh A, Singh A, Paliwal P, Mehdii SH.   +5 more
europepmc   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Advanced imaging strategies in cardiac organoids: bridging the gap between structural complexity and functional analysis. [PDF]

Cardiovasc Diabetol
Zhao K, Tang B, Gu R, Liu C, Zhang H, Gao Y, Wang P, Gu Y, Shi M, Li Z.   +9 more
europepmc   +1 more source

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, EarlyView.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Clinically relevant radiation therapy doses and obturation techniques modulate the adhesive performance of a resin-based sealer: interfacial integrity and bond strength analyses. [PDF]

Clin Oral Investig
Pandolfo MT, de Lima Dias-Júnior LC, Paz Dotto ME, Minamisako MC, Rodrigues PM, Cábia NC, de Sousa Veiga B, do Prado M, da Silveira Teixeira C, da Fonseca Roberti Garcia L.   +9 more
europepmc   +1 more source

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

Advanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang, Chenxi Zhang, Ranran Luo, Qiuchi Wu, Pengchen Ren, Xinyu Liu, Yingying Luo, Zhongsheng Xu, Xiaojing He, Yun Liu   +9 more
wiley   +1 more source

Effect of the antidepressant drug paroxetine in downregulating the biofilm-adhering genes in Staphylococcus aureus: In vitro and in silico studies. [PDF]

Medicine (Baltimore)
AlKhalidi HM, Ali AH, Abo-Ouf AM, El-Bidawy MH, Arafah AMR, Aldawsari SM, Dayel SB, Hajelbashir MI, Abd El-Naem MM, AlGhamdi MAA, Alhumaid KH, Abd El-Lateef AES, Aljabr KHE, Khairy HA, Samhan MA.   +14 more
europepmc   +1 more source

Multi‐Level Confinement Single‐Molecule Charge Transfer Activated PRET for Near‐Infrared Targeted Cell Imaging

Advanced Science, EarlyView.
The cascade supramolecular assembly of charge‐transfer arrays not only triggered a topological transformation from nanofiber to nanorod and vesicles, but also promoted single‐molecule phosphorescent resonance energy transfer, expanding phosphorescence emission at 500 nm to near‐infrared delayed fluorescence emission at 650 nm with a lifetime of 11.20 ...
Zhuo Lei, Sai Li, Pei‐Ao Sun, Yong Chen, Xuejian Zhang, Yu Liu   +5 more
wiley   +1 more source

Interkingdom Biofilms Are Affected by Non-Antibiotic Strategies: In Vitro Study in Lubbock Chronic Wound Biofilm Model. [PDF]

Int J Mol Sci
Di Fermo P, Diban F, Di Campli E, Cellini L, Pinti M, Di Giulio M, Petrini M, D'Ercole S, Di Lodovico S.   +8 more
europepmc   +1 more source