Results 101 to 110 of about 149 (149)

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

open access: yesAdvanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge   +16 more
wiley   +1 more source

Transient Interdomain Interactions Modulate the Monomeric Structural Ensemble and Self‐Assembly of Huntingtin Exon 1

open access: yesAdvanced Science, EarlyView.
Polyglutamine (polyQ) tract expansion (≥ 36 amino acids) within the N‐terminal region of the Huntingtin protein (Httex1) causes Huntington's disease (HD), for which the underlying causes are not well‐understood. The authors performed computer simulations to understand the cause of HD at the molecular level.
Priyesh Mohanty   +2 more
wiley   +1 more source

Enhanced Electrical Performance and Stretchability by Plasticizer‐Facilitated PEDOT:PSS Self‐Alignment

open access: yesAdvanced Science, EarlyView.
To advance stretchable electronics, understanding how organic plasticizers influence poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) morphology and conductivity remains crucial. A bilayer model with glycerol‐infused poly(vinyl alcohol) (PVA) substrates reveals that plasticizer diffusion reorganizes PEDOT and PSS, improving ...
Carla Volkert   +7 more
wiley   +1 more source

Light‐Driven PAA Adhesive: A Green Bonding Platform Integrating High‐Performance, Environmental Resilience, and Closed‐Loop Recyclability

open access: yesAdvanced Science, EarlyView.
This investigation introduces the formulation of a cutting‐edge, robust polyacrylic aqueous adhesive (PAA), synthesized through the employment of visible‐light initiated polymerization. The adhesive demonstrates minimal energy demand, environmental friendliness, robust adhesive properties (20.86 MPa on wood), remarkable thermal stability (with ...
Xueying Fu   +7 more
wiley   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu   +8 more
wiley   +1 more source

Dynamic Bonds Reinforced Polyamide Elastomer for Biomedical Orthosis

open access: yesAdvanced Science, EarlyView.
A dynamic bonds (DBs) reinforced shape memory polyamide elastomer is developed using reactive extrusion. Dynamic covalent networks enhance interlayer adhesion in 4D‐printed objects by utilizing the combined effects of multiple DBs, reducing mechanical anisotropy and improving the mechanical and shape memory properties.
Zhen Li   +12 more
wiley   +1 more source

Wireless Technologies for Wearable Electronics: A Review

open access: yesAdvanced Electronic Materials, EarlyView.
This review discusses recent advancements in wireless wearable electronics, focusing on communication technologies and power solutions. It covers key design considerations, explores wireless protocols from short‐ to long‐range networks, and examines powering methods such as integrated sources and energy harvesting.
Choong Yeon Kim   +8 more
wiley   +1 more source

Materials Selection Principles for Designing Electro‐Thermal Neurons

open access: yesAdvanced Electronic Materials, EarlyView.
Materials property – performance relations are established for new and old electrical materials leveraged as electro‐thermal oscillators emulating neuron dynamics. Robust, reconfigurable, high frequency, low power characteristics are explicitly tied to highly nonlinear electrical transport, small specific heat, and greater electrical than thermal ...
Fatme Jardali   +6 more
wiley   +1 more source

Wearable Image‐Based Colorimetric Sensor for Real‐Time Gas Detection with High Chromaticity

open access: yesAdvanced Electronic Materials, EarlyView.
Flexible colorimetric gas sensing offers energy‐free operation, intuitive feedback, and stability against environmental changes. This study presents a resonator‐based sensor integrated with polyvinyl alcohol (PVA) on a flexible substrate, achieving nearly full RGB coverage and angular robustness up to 60°.
Ji‐Eun Yeo   +3 more
wiley   +1 more source

Photo‐Thermal Approaches on Polyimide Film for Demonstration of Sub‐50 µm Polymer Stencil Mask

open access: yesAdvanced Electronic Materials, EarlyView.
A photo‑thermal approach enables precise control of polyimide film properties during UV laser processing, achieving stencil mask fabrication with feature dimensions <50 µm—with the smallest features measuring 42.4 µm. This method maintains the polymer in its glassy state during processing, resulting in exceptional pattern stability and reproducibility.
Bon‐Jae Koo   +6 more
wiley   +1 more source

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