Results 1 to 10 of about 3,781,135 (297)

For a Correct Application of the CD Exciton Chirality Method: The Case of Laucysteinamide A

Marine Drugs, 2018
The circular dichroism (CD) exciton chirality method (ECM) is a very popular approach for assigning the absolute configuration (AC) of natural products, thanks to its immediacy and ease of application.
Gennaro Pescitelli
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Mechanical control of molecular machines at an air–water interface: manipulation of molecular pliers, paddles

Science and Technology of Advanced Materials
Many artificial molecular machines have been synthesized, and various functions have been expressed by changing their molecular conformations. However, their structures are still simple compared with those of biomolecular machines, and more energy is ...
Taizo Mori
doaj   +1 more source

Effect of Tween 80 and Acetone on the Secretion, Structure and Antioxidant Activities of Exopolysaccharides from Lentinus tigrinus

Food Technology and Biotechnology, 2016
In this study, the effects of the addition of Tween 80 and acetone on secretion, structure and antioxidant activities of Lentinus tigrinus exopolysaccharides (EPS) were investigated.
Peixin He, Shuangshuang Wu, Lige Pan, Siwen Sun, Duobin Mao, Chunping Xu   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Research Progress on Conformational Polymorphism of Flexible Chain Molecules: Solid-State Structures, Regulation Strategies, and Functional Correlations

Pharmaceutical Fronts
This review aims to elucidate the mechanisms underlying conformational changes of drug molecules during crystallization and to investigate how these changes affect the physicochemical properties and biological characteristics of pharmaceuticals.
Gang Li, Hanbin Shan, Jiawei Hou, Jingming Yang, Yayi Hu, Hongjuan Pan, Hongbo Wang, Jialiang Zhong   +7 more
doaj   +1 more source

Crystal structure and conformational analysis of 2-hydroxy-3-(2-methylprop-1-en-1-yl)naphthalene-1,4-dione

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the structure of the title compound, C14H12O3, the substituent side chain, in which the H atoms of both methyl groups are disordered over six equivalent sites, lies outside of the plane of the naphthalenedione ring.
Sannyele Alcantara Emiliano, Sheyla Welma Duarte Silva, Mariano Alves Pereira, Valeria R.dos Santos Malta, Tatiane Luciano Balliano   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Crystal structures of the recreational drug N-(4-methoxyphenyl)piperazine (MeOPP) and three of its salts

Acta Crystallographica Section E: Crystallographic Communications, 2020
Crystal structures are reported for N-(4-methoxyphenyl)piperazine (MeOPP), (I), and for its 3,5-dinitrobenzoate, 2,4,6-trinitrophenolate (picrate) and 4-aminobenzoate salts, (II)–(IV), the last of which crystallizes as a monohydrate. In MeOPP, C11H16N2O,
Haruvegowda Kiran Kumar, Hemmige S. Yathirajan, Chayanna Harish Chinthal, Sabine Foro, Christopher Glidewell   +4 more
doaj   +1 more source

molecular conformation

, 2014
Citation: 'molecular conformation' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03984 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source