Results 181 to 190 of about 1,318 (279)

Conformable derivative operator in solving nonlinear fractional order differential equations

open access: yes
Yüksek Lisans TeziLiteratürde, geleneksel denklemlerden farklı olarak daha karmaşık olayları daha doğru bir şekilde modelleme yetenekleri nedeniyle doğrusal olmayan kesirli diferansiyel denklemler üzerine yoğunlaşılmakta ve bu denklemler için analitik ve
Yadigar, Muhammed Mustafa
core  

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding   +5 more
wiley   +1 more source

Automated Dynamic Flow Experimentation for Rapid Kinetic Fitting of Transition Metal Catalysis

open access: yesAngewandte Chemie, EarlyView.
We have developed an automated dynamic flow experimentation platform to automatically fit and identify the most accurate kinetic model from a generated set of candidates. Three transition metal‐catalyzed transformations were performed using this workflow.
Florian L. Wagner   +3 more
wiley   +2 more sources

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Expanding High‐Fidelity Multiplexing in Ultrasensitive Single‐Molecule Protein Detection via Proximity Barcoding

open access: yesAngewandte Chemie, EarlyView.
We develop an ultrasensitive, high‐accuracy multiplex protein detection platform integrating high‐throughput single‐molecule protein detection with proximity ligation. Using paired DNA barcodes, this platform breaks the digital immunoassay multiplexing ceiling imposed by cross‐reactivity and fluorescence spectral overlap, providing a broadly accessible
Chi‐Chia Wang, Emily Dorsey, Connie Wu
wiley   +2 more sources

Metal‐free Hydrogen Generation from Seawater and Silicon Waste: A Circular Approach

open access: yesAngewandte Chemie, EarlyView.
Hydrogen was rapidly generated directly from untreated seawater and polymeric Si waste without any transition metal catalyst. The in situ generated polymeric cross‐linked Si resin was completely depolymerized under mild conditions into chloro‐silane monomers.
Mustapha Hamdaoui   +6 more
wiley   +2 more sources

Gold(III) Semiquinone Complexes: Synthesis, Structure, and Application in Photocatalysis

open access: yesAngewandte Chemie, EarlyView.
Au(III) catecholate complexes engage into electron donor acceptor (EDA) interactions with aryldiazonium salts, enabling single‐electron transfer under green light irradiation. Ligand‐centered one‐electron oxidation to stable semi‐quinone complexes provides a new platform for standalone Au(III) photoredox catalysis, as substantiated by the C–H arylation
Miguel A. Gonzálvez   +8 more
wiley   +2 more sources

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