Results 51 to 60 of about 1,393,142 (267)

Design of Conformal Cooling System with Lattice-structure of Mold Based on 3D Printing

Journal of Physics: Conference Series, 2023
The conformal cooling water circuit manufactured by using metal 3D printing SLM technology has significant advantages, compared to the straight drilling cooling water circuit, but there is still a problem of large temperature differences in local mold ...
Caoxi Zhao, Zhong Chu, Hui Kang, Zihan Ni, Zhitong Li, Jicong Zhang   +5 more
semanticscholar   +1 more source

Cooling simulation of conformal cooling injection mould insert produced by hybrid manufacturing

Tehnicki vjesnik - Technical Gazette, 2017
Cooling of injection moulds manufactured by machining has limitations because cooling channels are formed by conventional straight holes. With additive manufacturing, the cooling channels can be produced in the shape which is adjusted to the cavity and core surface of injection moulds.
David Homar, Luka Čerče, Janez Kopač
openaire   +3 more sources

Structural Analysis of Molds with Conformal Cooling Channels: A Numerical Study

Engineering Proceedings, 2023
This article presents noteworthy discoveries pertaining to molds, featuring innovative conformal cooling channel designs. The aim of this study is to determine the upper limit of pressure that the components can endure in a real-world injection molding ...
Hugo Miguel Silva, João Tiago Noversa, Hugo Luís Rodrigues, Leandro Fernandes, António José Pontes   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Optimizing Laser Sintering Parameters and Cooling Channel Designs for Enhanced Injection Molding of Medical Tube Connectors

Journal of Applied Science and Engineering
Respiratory equipment disconnections in hospitals pose severe risks, including hypoxia and mortality. Suboptimal tube connector quality, often worsened by traditional cooling mold designs, results in uneven thermal equilibrium, product deformation, and ...
Ding Yang Hsu
doaj   +1 more source

Additively manufactured flexible on-package phased array antennas for 5G/mmWave wearable and conformal digital twin and massive MIMO applications

Scientific Reports, 2023
This paper thoroughly investigates material characterization, reliability evaluation, fabrication, and assembly processes of additively manufactured flexible packaging and reconfigurable on-package antenna arrays for next-generation 5G/mmWave wearable ...
Kexin Hu, Yi Zhou, Suresh K. Sitaraman, Manos M. Tentzeris   +3 more
doaj   +1 more source

Design, Characterisation and Numerical Investigations of Additively Manufactured H10 Hybrid-Forging Dies with Conformal Cooling Channels

Metals, 2022
Internal die cooling during forging can reduce thermal loads, counteracting surface softening, plastic deformation and abrasive die wear. Additive manufacturing has great potential for producing complex geometries of the internal cooling channels.
Bernd-Arno Behrens, Aziz Huskic, Daniel Rosenbusch, Julius Peddinghaus, Hendrik Wester, Martin Siegmund, Jochen Giedenbacher, Janina Siring   +7 more
doaj   +1 more source

Newton’s law of cooling with fractional conformable derivative

Revista Mexicana de Física, 2018
The fractional conformable derivative and its properties have been introduced recently. Using this derivative we obtain a new class of smooth solutions for the Newton’s law of cooling in terms of a stretched exponential function depending on the fractional order parameter 0 < γ ≤ 1.
Abraham Ortega, J. Juan Rosales
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source