Results 171 to 180 of about 4,829,113 (325)

On Distortion at the Boundary of a Conformal Map [PDF]

Proceedings of the National Academy of Sciences, 1950
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A skin-conformal rigid-in-soft array-based imaging system. [PDF]

Nat Commun
Yuan X, Zhang J, Liu Y, Wang Y, Fang L.
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Machine learning-based geospatial assessment of forest structure characteristics and sequestration potential for informed carbon stocks inventories. [PDF]

Sci Rep
Tasuev U, Tregubova P, Illarionova S, Shadrin D, Bernshteyn A, Burnaev E.   +5 more
europepmc   +1 more source

China proper SE 1:250,000 [cartographic material] /

, 1944
Map series of the southeastern corner of China showing international, province and district boundaries, transportation, water features, walls, rice fields and populated places.
United States. Army Map Service.
core  

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

GiantHost: a domain-adaptive and uncertainty-aware framework for giant virus host prediction. [PDF]

Bioinformatics
Qu F, Chen G, Sun Y.
europepmc   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Lithographic patterning of conformal thin films on 3D structures using Scaffold-architected Lift-off masks. [PDF]

Nat Commun
Liu X, Che Z, Maj Z, Lai LL, Gylfason KB, Dubois V, N Raja S, Stemme G, Niklaus F.   +8 more
europepmc   +1 more source