Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
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Intelligent <i>in-silico</i> prioritization of antimalarial peptide candidates under explicit physicochemical windows via <i>de novo</i> CTCM-Neo generation and conformal-gated calibrated classification. [PDF]
Aamir M, Rezaee K, Anari MS.
europepmc +1 more source
A soft, dual‐channel hydrogel patch enables simultaneous detection of wound temperature and strain by integrating ion‐diffusion‐mediated thermoelectric and resistive sensing. The conformal design maintains stable performance during motion, capturing subtle inflammatory and mechanical changes for continuous wound monitoring.
Yu Fang +7 more
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Aberration corrections for quasi-conformal transformation optics-based reflectors. [PDF]
Cross B, Friedrichs G, Filipovic D.
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Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar +5 more
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Foundation and Multimodal Models for Drug Discovery in Molecular Informatics: Principles, Evaluation, and Practical Guidance. [PDF]
Pastore EP, De Rango F.
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Tough Injectable Hydrogels Enabled by Integrating Rigid Homogeneous Framework With Flexible Chains
Tough injectable hydrogels are constructed by integrating a rigid, homogeneous hyaluronic acid framework with flexible long‐chain connectors. This framework–flexible structure simultaneously enhances network uniformity and promotes effective energy dissipation by enlarging plastic deformation zones under compression.
Rijian Song +10 more
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Machine learning prediction and calibration of cellulose-based solid-phase extraction performance for pharmaceuticals across aqueous matrices. [PDF]
Akor E +4 more
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A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Cross-Modal Interaction Fusion-Based Uncertainty-Aware Prediction Method for Industrial Froth Flotation Concentrate Grade by Using a Hybrid SKNet-ViT Framework. [PDF]
Lu F, Gui W, Wang Y, Zhou J, Wang X.
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