Results 51 to 60 of about 90,774 (312)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
On Makarov’s Principle in Conformal Mapping [PDF]
International Mathematics Research Notices, 2017 20 ...
openaire +6 more sources
Conformal Mappings in Relativistic Astrophysics [PDF]
Journal of Applied Mathematics, 2013 We describe the use of conformal mappings as a mathematical mechanism to obtain exact solutions of the Einstein field equations in general relativity. The behaviour of the spacetime geometry quantities is given under a conformal transformation, and the Einstein field equations are exhibited for a perfect fluid distribution matter configuration.
S. Hansraj, K. S. Govinder, N. Mewalal
openaire +3 more sources
Laplacian transfer across a rough interface: Numerical resolution in the conformal plane
, 2005 We use a conformal mapping technique to study the Laplacian transfer across a rough interface. Natural Dirichlet or Von Neumann boundary condition are simply read by the conformal map.
Damien Vandembroucq +9 more
core +2 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The Moebius geometry of Wintgen ideal submanifolds [PDF]
, 2014 Wintgen ideal submanifolds in space forms are those ones attaining equality pointwise in the so-called DDVV inequality which relates the scalar curvature, the mean curvature and the scalar normal curvature. They are Moebius invariant objects.
Ma, Xiang, Xie, Zhenxiao
core
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source