Results 231 to 240 of about 1,518,966 (331)

Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units

Biopolymers, 1968
I. C
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

BacA(SbmA) importer of legume symbiotic NCR peptides: Protein architecture, function, and evolutionary implications. [PDF]

Proc Natl Acad Sci U S A
Arnold MFF, Sankari S, Deutsch M, Gruber CC, Guerra-Garcia FJ, Beis K, Walker GC.   +6 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Monitoring ADAMTS-13 conformation in immune-mediated thrombotic thrombocytopenic purpura: toward personalized management. [PDF]

Res Pract Thromb Haemost
Joly BS, Roose E, Dekimpe C, Vanhoorelbeke K, Veyradier A, Coppo P.   +5 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Critical structural perturbations of ribozyme active sites induced by 2'-O-methylation commonly used in structural studies. [PDF]

Nucleic Acids Res
Forget S, Stirnemann G.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Structural analysis of rhodopsin states in megabody complexes. [PDF]

Proc Natl Acad Sci U S A
Salom D, Suder DS, Huang W, Wu A, Pardon E, Steyaert J, Kiser PD, Taylor DJ, Gonen S, Palczewski K.   +9 more
europepmc   +1 more source

Conformative Coupling of Two Conformational Molecular Switches

Angewandte Chemie International Edition, 2003
Karle, M., Bockelmann, D., Schumann, D., Griesinger, C., Koert, U.   +4 more
openaire   +4 more sources