Results 271 to 280 of about 1,518,966 (331)

Structural basis for substrate-dependent allostery in oxygen activation by a cytochrome P450 enzyme revealed by analysis at different temperatures. [PDF]

Chem Sci
Podgorski MN, McDougal DP, Campbell EC, Bruning JB, Bell SG.   +4 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Efficient sampling of large-scale transition pathways and intermediate conformations in sub-mesoscopic protein complexes. [PDF]

Nat Commun
Scaramozzino D, Lee BH, Orellana L.
europepmc   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Study of Calcitriol Interaction with the Vitamin D Receptor Using DFT and TD-DFT Calculations. [PDF]

J Phys Chem B
Miranda VR, Morgon NH.
europepmc   +1 more source

Molecular foundations of collagen triple helical assembly: the central role of prolyl-4-hydroxylation. [PDF]

Biochem J
Joshi A, Mondal B, Basak T.
europepmc   +1 more source

Regulation and activity of the phosphatase SHP2: SH2 domains, dephosphorylation activity, and beyond. [PDF]

Biochem Soc Trans
Pierotti CL, Köhn M.
europepmc   +1 more source

Non-Conjugated Linear Polysiloxane with Cluster-Triggered Circularly Polarized Luminescence. [PDF]

JACS Au
Yu HC, Mure T, Shinoda T, Lu CS, Terami K, Morii S, Li SH, Hirai T, Li MC.   +8 more
europepmc   +1 more source

Structural basis for the allosteric regulation and catalytic mechanism of Staphylococcus aureus UMP kinase. [PDF]

Front Microbiol
Gao Y, Zhu Z, Wang L, Ke J, Niu L.
europepmc   +1 more source

An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]

J Biol Chem
Marcus K, Schwabe M, Knihtila R, Mattos C.   +3 more
europepmc   +1 more source