Results 31 to 40 of about 1,518,966 (331)
Conformation Sensitive Targeting of Lipid Nanoparticles for RNA Therapeutics
Nature Nanotechnology, 2021 The successful in vivo implementation of gene expression modulation strategies relies on effective, non-immunogenic delivery vehicles. Lipid nanoparticles are one of the most advanced non-viral clinically approved nucleic-acid delivery systems. Yet lipid
Niels Dammes +6 more
semanticscholar +1 more source
Biomolecules, 2019 De novo protein synthesis by the ribosome and its multitude of co-factors must occur in a tightly regulated manner to ensure that the correct proteins are produced accurately at the right time and, in some cases, also in the proper location.
Kelvin K. Hui +3 more
doaj +1 more source
Controlling the SARS-CoV-2 spike glycoprotein conformation
Nature Structural & Molecular Biology, 2020 The coronavirus (CoV) spike (S) protein, involved in viral–host cell fusion, is the primary immunogenic target for virus neutralization and the current focus of many vaccine design efforts. The highly flexible S-protein, with its mobile domains, presents
R. Henderson +12 more
semanticscholar +1 more source
Genome-wide Translation Profiling by Ribosome-Bound tRNA Capture
Cell Reports, 2018 Summary: In the ribosome complex, tRNA is a critical element of mRNA translation. A rich repertoire of cell regulation is hypothesized to occur during the recruitment of specific tRNAs in polypeptide formation.
Chien-Wen Chen, Motomasa Tanaka
doaj +1 more source
Molecular flexibility of citrus pectins by combined sedimentation and viscosity analysis [PDF]
, 2007 The flexibility/rigidity of pectins plays an important part in their structure-function relationship and therefore on their commercial applications in the food and biomedical industries.
Alan Smith +47 more
core +1 more source
Living Reviews in Relativity, 2000 The notion of conformal infinity has a long history within the research in Einstein's theory of gravity. Today, "conformal infinity" is related to almost all other branches of research in general relativity, from quantisation procedures to abstract mathematical issues to numerical applications.
openaire +8 more sources
Coil-helix transition of polypeptide at water-lipid interface [PDF]
, 2015 We present the exact solution of a microscopic statistical mechanical model for the transformation of a long polypeptide between an unstructured coil conformation and an $\alpha$-helix conformation.
Andreev, Oleg A. +4 more
core +3 more sources
Applying mesh conformation on shape analysis with missing data [PDF]
, 2004 A mesh conformation approach that makes use of deformable generic meshes has been applied to establishing correspondences between 3D shapes with missing data.
Ju, X. +5 more
core +1 more source
A chromosome conformation capture ordered sequence of the barley genome
Nature, 2017 Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually ...
M. Mascher +75 more
semanticscholar +1 more source
Accuracy of generic mesh conformation: the future of facial morphological analysis [PDF]
, 2017 Three-dimensional (3D) analysis of the face is required for the assessment of changes following surgery, to monitor the progress of pathological conditions and for the evaluation of facial growth.
Almukhtar, A. +4 more
core +2 more sources