Results 151 to 160 of about 3,678,372 (337)

Protein conformational dynamics and phenotypic switching

open access: yesBiophysical Reviews, 2021
Prakash Kulkarni   +10 more
semanticscholar   +1 more source

LOCALLY CONFORMAL HIGHER ORDER LAGRANGIAN DYNAMICS

open access: yesProceedings of the Institute of Mathematics and Mechanics, National Academy of Sciences of Azerbaijan
This work presents higher order Lagrangian dynamics possessing locally conformal character. More concretely, locally conformal higher order Euler-Lagrange equations are written with particular focus on the second- and the third-order cases.
Çite, Serdar, Esen, Oğul
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Role of Conformational Dynamics in the Evolution of Retro-Aldolase Activity

open access: yesACS Catalysis, 2017
Enzymes exist as ensembles of conformations that are important for function. Tuning these populations of conformational states through mutation enables evolution toward additional activities. Here we computationally evaluate the population shifts induced
A. Romero‐Rivera   +2 more
semanticscholar   +1 more source

TALEs from a spring -- superelasticity of Tal effector protein structures

open access: yes, 2014
A simple force-probe setup is employed to study the mechanical properties of transcription activator-like effector (TALE) proteins in computer experiments. It is shown that their spring-like arrangement benefits superelastic behaviour which is manifested
Flechsig, Holger
core   +3 more sources

Conformational dynamics of the pyrene excimer

open access: yesPhysical Chemistry Chemical Physics
We characterized the S 1 state PES of the pyrene dimer, revealing key excimer conformations. A rapid shift to a stacked-twisted form dominates the excimer's structure and fluorescence.
Giovanni Parolin   +5 more
openaire   +4 more sources

Coarse expanding conformal dynamics

open access: yesAstérisque, 2018
Building on the dictionary between Kleinian groups and rational maps, we establish new connections between the theories of hyperbolic groups and certain iterated maps, regarded as dynamical systems. In order to make the exposition self-contained to researchers in many fields, we include detailed proofs and ample background.
Haïssinsky, Peter, Pilgrim, Kevin
openaire   +3 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Plasmon Rulers as a Probe for Real-Time Microsecond Conformational Dynamics of Single Molecules

open access: yesNano letters (Print), 2018
Biopolymers such as DNA, RNA, and proteins exploit conformational changes to modulate their function. Although state-of-the-art single-molecule approaches enable identification of conformational states, the transition path and metastable intermediates ...
Emiel W. A. Visser   +2 more
semanticscholar   +1 more source

Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations [PDF]

open access: yes, 2006
Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions.
Engels, Joachim W. (Prof. Dr.)   +1 more
core  

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