Results 191 to 200 of about 3,454,137 (301)

Conformational Dynamics of Amylin Receptors Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. [PDF]

J Am Chem Soc
Fairweather CJ, Zhang X, Fernando CD, Garama DJ, Sexton PM, Wootten D, Josephs TM.   +6 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Conformally symplectic Dynamics

Dynamists have been studying Hamiltonian systems for a long time. However, many physical systems are dissipative and do not preserve a symplectic form. This is the case, for example, with systems involving friction, which multiply the symplectic form by a constant smaller than 1. We will prove that almost every point is in the unstable set of infinity
openaire   +2 more sources

Protein Conformational Dynamics Preface

, 2014
Zhang, Xin, Han, KL, Han, Ke-li, Yang, Ming-jun, Yang, MJ, Zhang, X   +5 more
core  

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

Advanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer, H. Mutlu, C. Charmette, E. Randrianaridera, Z. Adaidi, R. Hedna, L. Pieuchot, I. Pluvy, K. Anselme, N. Couturier, J. P. Mericq, A. Ponche, I. Brigaud   +12 more
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides. [PDF]

Proteins
Kidman KA, Pedrick C, Kreck CA, Mancera RL.   +3 more
europepmc   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity. [PDF]

Elife
Mancl JM, Liang WG, Bayhi NL, Wei H, Budell WC, Mendez JH, Sosnick TR, Carragher B, Potter CS, Potter CS, Tang WJ.   +10 more
europepmc   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters. [PDF]

J Biol Chem
Jafari M, Zhao H, Zhang Y, Wang T, Merz KM, Hu J.   +5 more
europepmc   +1 more source