Results 21 to 30 of about 1,168,249 (276)

Preanalytical confounding factors in the analysis of cerebrospinal fluid biomarkers for Alzheimer’s disease: the issue of diurnal variation

Frontiers in Neurology, 2015
Given the growing use of cerebrospinal fluid (CSF) beta-amyloid (Aβ) and tau as biomarkers for early diagnosis of Alzheimer’s disease (AD), it is essential that the diagnostic procedures are standardized and the results comparable across different ...
Claudia eCicognola, Davide eChiasserini, Lucilla eParnetti   +2 more
doaj   +1 more source

Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]

, 2015
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta, De Vos, Martine, Laukens, Debby, Raes, Jeroen, Vandenabeele, Peter   +4 more
core   +1 more source

Analysis of matched case-control studies. [PDF]

, 2016
© BMJ Publishing Group Ltd 2015. There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a "matched analysis" is ...
Pearce, Neil
core   +1 more source

Confounding Factor Analysis for Vocal Fold Oscillations

Entropy, 2023
This paper provides a methodology to better understand the relationships between different aspects of vocal fold motion, which are used as features in machine learning-based approaches for detecting respiratory infections from voice recordings. The relationships are derived through a joint multivariate analysis of the vocal fold oscillations of ...
openaire   +4 more sources

Recommendations for using standardised phenotypes in genetic association studies

Human Genomics, 2009
Genetic association studies of complex traits often rely on standardised quantitative phenotypes, such as percentage of predicted forced expiratory volume and body mass index to measure an underlying trait of interest (eg lung function, obesity).
Naylor Melissa G, Weiss Scott T, Lange Christoph   +2 more
doaj   +1 more source

Can a simple measure of vigorous physical activity predict future mortality? Results from the OXCHECK study. [PDF]

, 2004
BACKGROUND: As epidemiological studies have become more complex, demands for short, easily administered measures of risk factors have increased. This study investigates whether such a measure of physical activity is associated with the risk of death from
Hillsdon, Melvyn, Jones, Lesley, Murphy, Mike, Thorogood, Margaret   +3 more
core   +2 more sources

Iron Metabolism in Children: Confounding Factors [PDF]

Food and Nutrition Bulletin, 2007
Characterization of iron metabolism in infants and children may be confounded by the diverse effects of developmental, genetic, and acquired influences on iron metabolism and laboratory measurements of iron status, especially in areas with intense perennial transmission of Plasmodium falciparum malaria. In the Pemba iron and folic acid supplementation
openaire   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Bacterial genome-wide association studies: exploring the genetic variation underlying bacterial phenotypes

Applied and Environmental Microbiology
With the continuous advancements in high-throughput genome sequencing technologies and the development of innovative bioinformatics tools, bacterial genome-wide association studies (BGWAS) have emerged as a transformative approach for investigating the ...
Qiuping Yang, Xiaoqi Wang, Mengting Han, Huanjing Sheng, Yulu Sun, Li Su, Wenjing Lu, Mei Li, Siyue Wang, Jia Chen, Shenghui Cui, Bao-Wei Yang   +11 more
doaj   +1 more source

Adjusting for Confounding by Neighborhood Using a Proportional Odds Model and Complex Survey Data [PDF]

, 2011
In social epidemiology, an individual\u27s neighborhood is considered to be an important determinant of health behaviors, mediators, and outcomes. Consequently, when investigating health disparities, researchers may wish to adjust for confounding by ...
Brumback, Babette A., Dailey, Amy B., Zheng, Hao W.   +2 more
core   +2 more sources