Results 31 to 40 of about 8,216,381 (305)

Preanalytical confounding factors in the analysis of cerebrospinal fluid biomarkers for Alzheimer’s disease: the issue of diurnal variation

Frontiers in Neurology, 2015
Given the growing use of cerebrospinal fluid (CSF) beta-amyloid (Aβ) and tau as biomarkers for early diagnosis of Alzheimer’s disease (AD), it is essential that the diagnostic procedures are standardized and the results comparable across different ...
Claudia eCicognola, Davide eChiasserini, Lucilla eParnetti   +2 more
doaj   +1 more source

Accurate modeling of confounding variation in eQTL studies leads to a great increase in power to detect trans-regulatory effects [PDF]

, 2011
Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or ...
Neil Lawrence, Oliver Stegle, Nicolo Fusi   +2 more
core  

Confounding factors for ΔT.

, 2018
Confounding factors for ΔT.
Jose Luis Ramirez-GarciaLuna (3873601), Mario Aurelio Martínez-Jiménez (5963564), Eleazar Samuel Kolosovas-Machuca (5963567), Justin Drager (5963570), Francisco Javier González (5963573)   +4 more
core   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Athlete biological passport: longitudinal biomarkers and statistics in the fight against doping

Arhiv za Higijenu Rada i Toksikologiju
As novel substances, short time windows, and limits of detection increasingly challenge direct methods of doping detection in sports, indirect tools inevitably take a greater role in the fight against it. One such tool is the athlete biological passport (
Dragčević Dora, Pandžić Jakšić Vlatka, Jakšić Ozren   +2 more
doaj   +1 more source

Oral finasteride use and sexual adverse events: signal detection from disproportionality analyses of data from the United States Food and Drug Administration Adverse Event Reporting System

Journal of Dermatological Treatment
Background Oral finasteride 1 milligram (1 mg) daily—which is a 5-alpha reductase inhibitor (5-ARI) approved by the Food and Drug Administration (FDA) for androgenetic alopecia—is linked to sexual adverse events (AEs). However, it remains unclear whether
Aditya K. Gupta, Mesbah Talukder, Greg Williams, Mary A. Bamimore   +3 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The influence of the maternal microbiome on offspring neurodevelopment: a critical review of associations, controversies, and challenges

Frontiers in Neuroscience
The role of the maternal microbiome in offspring neurodevelopment has become a prominent topic in neuroscience, yet its true causal status is under intense scrutiny.
Hua Bai, Yan Xu, Shen Qu, Borui Li, Xinna Wang   +4 more
doaj   +1 more source

Methods for Population-Based eQTL Analysis in Human Genetics

Tsinghua Science and Technology, 2014
Gene expression is a critical process in biological system that is influenced and modulated by many factors including genetic variation. Expression Quantitative Trait Loci (eQTL) analysis provides a powerful way to understand how genetic variants affect ...
Lu Tian, Andrew Quitadamo, Frederick Lin, Xinghua Shi   +3 more
doaj   +1 more source