Results 21 to 30 of about 1,191,463 (297)

Recommendations for using standardised phenotypes in genetic association studies

Human Genomics, 2009
Genetic association studies of complex traits often rely on standardised quantitative phenotypes, such as percentage of predicted forced expiratory volume and body mass index to measure an underlying trait of interest (eg lung function, obesity).
Naylor Melissa G, Weiss Scott T, Lange Christoph   +2 more
doaj   +1 more source

Predicting Adoption Probabilities in Social Networks

, 2013
In a social network, adoption probability refers to the probability that a social entity will adopt a product, service, or opinion in the foreseeable future.
Fang, Xiao, Hu, Paul J., Li, Zhepeng, Tsai, Weiyu   +3 more
core   +1 more source

Geographic bias related to geocoding in epidemiologic studies

International Journal of Health Geographics, 2005
Background This article describes geographic bias in GIS analyses with unrepresentative data owing to missing geocodes, using as an example a spatial analysis of prostate cancer incidence among whites and African Americans in Virginia, 1990–1999 ...
Siadaty Mir, Matthews Kevin A, Oliver M Norman, Hauck Fern R, Pickle Linda W   +4 more
doaj   +1 more source

Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]

, 2015
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta, De Vos, Martine, Laukens, Debby, Raes, Jeroen, Vandenabeele, Peter   +4 more
core   +1 more source

Confounding Factor Analysis for Vocal Fold Oscillations

Entropy, 2023
This paper provides a methodology to better understand the relationships between different aspects of vocal fold motion, which are used as features in machine learning-based approaches for detecting respiratory infections from voice recordings. The relationships are derived through a joint multivariate analysis of the vocal fold oscillations of ...
openaire   +4 more sources

Iron Metabolism in Children: Confounding Factors [PDF]

Food and Nutrition Bulletin, 2007
Characterization of iron metabolism in infants and children may be confounded by the diverse effects of developmental, genetic, and acquired influences on iron metabolism and laboratory measurements of iron status, especially in areas with intense perennial transmission of Plasmodium falciparum malaria. In the Pemba iron and folic acid supplementation
openaire   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Bacterial genome-wide association studies: exploring the genetic variation underlying bacterial phenotypes

Applied and Environmental Microbiology
With the continuous advancements in high-throughput genome sequencing technologies and the development of innovative bioinformatics tools, bacterial genome-wide association studies (BGWAS) have emerged as a transformative approach for investigating the ...
Qiuping Yang, Xiaoqi Wang, Mengting Han, Huanjing Sheng, Yulu Sun, Li Su, Wenjing Lu, Mei Li, Siyue Wang, Jia Chen, Shenghui Cui, Bao-Wei Yang   +11 more
doaj   +1 more source

Preanalytical confounding factors in the analysis of cerebrospinal fluid biomarkers for Alzheimer’s disease: the issue of diurnal variation

Frontiers in Neurology, 2015
Given the growing use of cerebrospinal fluid (CSF) beta-amyloid (Aβ) and tau as biomarkers for early diagnosis of Alzheimer’s disease (AD), it is essential that the diagnostic procedures are standardized and the results comparable across different ...
Claudia eCicognola, Davide eChiasserini, Lucilla eParnetti   +2 more
doaj   +1 more source

Accurate modeling of confounding variation in eQTL studies leads to a great increase in power to detect trans-regulatory effects [PDF]

, 2011
Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or ...
Neil Lawrence, Nicolo Fusi, Oliver Stegle   +2 more
core   +1 more source