Results 51 to 60 of about 1,191,463 (297)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SensorsMonitoring soil moisture (SM) using permanently installed gamma radiation (GR) detectors is a promising non-invasive method based on the inverse relationship between SM and soil-emitted GR.
Sonia Akter +2 more
doaj +1 more source
Frontiers in Neuroscience, 2017 A recent report claims that functional brain networks defined with resting-state functional magnetic resonance imaging (fMRI) can be recapitulated with correlated gene expression (i.e., high within-network tissue-tissue “strength fraction,” SF ...
Spiro P. Pantazatos +2 more
doaj +1 more source
Genome Biology, 2021 Clustering of joint single-cell RNA-Seq (scRNA-Seq) data is often challenged by confounding factors, such as batch effects and biologically relevant variability.
Zhiyuan Hu +2 more
doaj +1 more source
Quantifying and estimating additive measures of interaction from case-control data
, 2017 In this paper we develop a general framework for quantifying how binary risk factors jointly influence a binary outcome. Our key result is an additive expansion of odds ratios as a sum of marginal effects and interaction terms of varying order.
Alfredsson, Lars +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Re-Examination of the Border Effect [PDF]
This paper reexamines the evidence on the border effect, the finding that the border drives a wedge between domestic and foreign prices. We argue that the border effect can be inflated by the volatility and persistence of the nominal exchange rate and by
Linda Tesar, Yuriy Gorodnichenko
core +3 more sources
Transparent and complete reporting of confounding in observational research
JCPP Advances, 2022 Improved understanding of causal risk factors for child and adolescent mental health problems are dependent on observational research. Although confounding is a major limitation of observational research, this problem is widely ignored in the reporting ...
Henrik Larsson
doaj +1 more source
Non-Parametric Causality Detection: An Application to Social Media and Financial Data [PDF]
, 2017 According to behavioral finance, stock market returns are influenced by emotional, social and psychological factors. Several recent works support this theory by providing evidence of correlation between stock market prices and collective sentiment ...
Musolesi, Mirco +2 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source