Results 61 to 70 of about 8,216,381 (305)
Transparent and complete reporting of confounding in observational research
Improved understanding of causal risk factors for child and adolescent mental health problems are dependent on observational research. Although confounding is a major limitation of observational research, this problem is widely ignored in the reporting ...
Henrik Larsson
doaj +1 more source
Identification of the human factors contributing to maintenance failures in a petroleum operation
Structured interviews (N=38) were conducted with maintainers in a petroleum company who were asked to discuss a maintenance failure with which they were familiar.
Ari Antonovsky +7 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An Open Path to DAG: Navigating Causal Inference in Epidemiological Research
Directed acyclic graphs (DAGs) are a valuable tool in epidemiology for illustrating causal relationships between variables in epidemiological research. DAGs enhance the transparency and robustness of the causal inference by delineating causal paths and ...
Navaneeth S. Krishna +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Background Fish consumption and intake of omega-3 fatty acids from fish are associated with a lower risk of cardiovascular disease. However, a prospective study from northern Sweden showed that high consumption of fish is associated with an increased ...
Wennberg Maria +5 more
doaj +1 more source
Relationship of confounding factors with respect to treatment groups.
Relationship of confounding factors with respect to treatment groups.
Tauqeer Hussain Mallhi (8720688) +8 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Association between air pollution and suicide: a time series analysis in four Colombian cities
Background Recent epidemiological studies have suggested that air pollution could be associated with suicide. However, other studies have criticized these results for being analytically weak and not taking into account potential confounding factors.
Julián Alfredo Fernández-Niño +3 more
doaj +1 more source

