Results 61 to 70 of about 762,252 (305)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Open Path to DAG: Navigating Causal Inference in Epidemiological Research

Indian Journal of Community Medicine
Directed acyclic graphs (DAGs) are a valuable tool in epidemiology for illustrating causal relationships between variables in epidemiological research. DAGs enhance the transparency and robustness of the causal inference by delineating causal paths and ...
Navaneeth S. Krishna, Madhanraj Kalyanasundaram, Tarun Bhatnagar   +2 more
doaj   +1 more source

Transparent and complete reporting of confounding in observational research

JCPP Advances, 2022
Improved understanding of causal risk factors for child and adolescent mental health problems are dependent on observational research. Although confounding is a major limitation of observational research, this problem is widely ignored in the reporting ...
Henrik Larsson
doaj   +1 more source

Assessment of Confounding Factors Affecting the Tumor Markers SMRP, CA125, and CYFRA21-1 in Serum

, 2010
The purpose of this analysis was to evaluate if serum levels of potential tumor markers for the diagnosis of malignant mesothelioma and lung cancer are affected by confounding factors in a surveillance cohort of workers formerly exposed to asbestos. SMRP,
Pesch, B., Isabelle Mercedes Gross, Thomas Kraus, Brüning, T., Thomas Brüning, Dirk Taeger, Gross, I. M., Kraus, Thomas, Johnen, G., Georg Johnen, Weber, A., Taeger, D., Gube, Monika, Thomas Brüning, Monika Gube, Weber, D. G., Daniel Gilbert Weber, Anne Weber, Beate Pesch   +18 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Confounding factors.

, 2013
The GlobalAncova analysis evaluates if the panel protein levels remain significantly differentiated between the acute rejection (AR) and the non-rejection (NR) groups after adjusting for potential confounding factors.
Mayu Sasaki (399179), Nina Opushneva (399180), Bruce McManus (128550), David Lin (399182), Axel Bergman (399178), Raymond T. Ng (253624), Janet Wilson-McManus (399183), Paul A. Keown (399185), Karen K. Y. Lam (165569), W. Robert McMaster (219114), Zsuzsanna Hollander (229895), Christoph H. Borchers (159697), Gabriela V. Cohen Freue (399175), Anna Meredith (399176), Robert Balshaw (399184), Derek Smith (399177), Mandeep Takhar (399181)   +16 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Diet and lifestyle factors associated with fish consumption in men and women: a study of whether gender differences can result in gender-specific confounding

Nutrition Journal, 2012
Background Fish consumption and intake of omega-3 fatty acids from fish are associated with a lower risk of cardiovascular disease. However, a prospective study from northern Sweden showed that high consumption of fish is associated with an increased ...
Wennberg Maria, Tornevi Andreas, Johansson Ingegerd, Hörnell Agneta, Norberg Margareta, Bergdahl Ingvar A   +5 more
doaj   +1 more source

Confounding Factors Influencing Amyloid Beta Concentration in Cerebrospinal Fluid [PDF]

, 2010
Background. Patients afflicted with Alzheimer's disease (AD) exhibit a decrease in the cerebrospinal fluid (CSF) concentration of the 42 amino acid form ofβ-amyloid (Aβ42).
Henrik Zetterberg, Anckarsäter, Rolf,, Blennow, Kaj,, Bjerke, Maria,, Andreasson, U, Anckarsäter, R, Andreasen, N,, Kaj Blennow, Blennow, K, Erik Portelius, Rolf Anckarsäter, Anders Wallin, Anckarsäter, H, Bjerke, M, Portelius, E, Ulf Andreasson, Niels Andreasen, Zetterberg, H, Maria Bjerke, Portelius, Erik,, Wallin, A, Zetterberg, Henrik,, Wallin, Anders,, Andreasen, Niels, Minthon, L, Andreasson, Ulf,, Anckarsäter, Henrik,, Lennart Minthon, Henrik Anckarsäter, Minthon, Lennart,   +29 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source