Results 61 to 70 of about 1,191,463 (297)

To Adjust or Not to Adjust? Sensitivity Analysis of M-Bias and Butterfly-Bias [PDF]

open access: yes, 2014
"M-Bias," as it is called in the epidemiologic literature, is the bias introduced by conditioning on a pretreatment covariate due to a particular "M-Structure" between two latent factors, an observed treatment, an outcome, and a "collider." This ...
Ding, Peng, Miratrix, Luke
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An Open Path to DAG: Navigating Causal Inference in Epidemiological Research

open access: yesIndian Journal of Community Medicine
Directed acyclic graphs (DAGs) are a valuable tool in epidemiology for illustrating causal relationships between variables in epidemiological research. DAGs enhance the transparency and robustness of the causal inference by delineating causal paths and ...
Navaneeth S. Krishna   +2 more
doaj   +1 more source

Breastfeeding shows a protective trend toward adolescents with higher abdominal adiposity [PDF]

open access: yes, 2014
Objective: The question of whether breastfeeding has a protective effect against the development of overweight or obesity later in life remains controversial, especially during adolescence.
De Henauw, Stefaan   +12 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Comorbidity and confounding factors in attention-deficit/hyperactivity disorder and sleep disorders in children

open access: yesPsychology Research and Behavior Management, 2011
Ya-Wen Jan1,2, Chien-Ming Yang1,3, Yu-Shu Huang4,51Department of Psychology, National Cheng-Chi University, Taipei; 2Sleep Center of Taipei Medical University Hospital, Taipei; 3The Research Center for Mind Brain and Learning, National Cheng-Chi ...
Huang YS, Yang CM, Jan YW
doaj  

Diet and lifestyle factors associated with fish consumption in men and women: a study of whether gender differences can result in gender-specific confounding

open access: yesNutrition Journal, 2012
Background Fish consumption and intake of omega-3 fatty acids from fish are associated with a lower risk of cardiovascular disease. However, a prospective study from northern Sweden showed that high consumption of fish is associated with an increased ...
Wennberg Maria   +5 more
doaj   +1 more source

Low radon exposures and lung cancer risk: joint analysis of the Czech, French, and Beaverlodge cohorts of uranium miners. [PDF]

open access: yes, 2019
It is well established that high radon exposures increase the risk of lung cancer mortality. The effects of low occupational exposures and the factors that confound and modify this risk are not clear and are needed to inform current radiation protection ...
Lane, Rachel SD   +5 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Association between air pollution and suicide: a time series analysis in four Colombian cities

open access: yesEnvironmental Health, 2018
Background Recent epidemiological studies have suggested that air pollution could be associated with suicide. However, other studies have criticized these results for being analytically weak and not taking into account potential confounding factors.
Julián Alfredo Fernández-Niño   +3 more
doaj   +1 more source

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