Results 211 to 220 of about 869,874 (249)

Impacts of COVID-19 on pediatric patients with congenital heart disease: a small systematic and integrative literature review. [PDF]

Rev Paul Pediatr
Oliveira AM, Cartøgenes AD, Berni LC, Amaral LMB, Machado RL, Oliveira RCS.   +5 more
europepmc   +1 more source

Anomalous Pattern of Left Hemisphere Visual Connectivity in Children With Autism: Association With Impaired Praxis

Autism Research, EarlyView.
ABSTRACT Prominent theories of autism suggest autism‐associated differences in visual‐motor integration (VMI) may disrupt learning of motor and social skills typically acquired by observation and imitation. Supporting these theories, children with autism spectrum disorder (ASD) show robust differences in motor tasks reliant on dynamic VMI (e.g., ball ...
Jonah McLaughlin, Deana Crocetti, Stewart H. Mostofsky, Daniel E. Lidstone   +3 more
wiley   +1 more source

Congenital anomalies after first-trimester dydrogesterone therapy during in vitro fertilization. [PDF]

Reprod Biol Endocrinol
Yang W, Zeng L, Chen L, Yang R, Wang H, Liu P, Lian Y, Li R, Chi H, Qiao J.   +9 more
europepmc   +1 more source

Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Atypical infant head circumference (HC)—including increased rates of macrocephaly and microcephaly—has been linked to autism spectrum disorder (ASD). However, specific head growth trajectories associated with ASD remain poorly defined. This retrospective case–control study aimed to delineate these trajectories and examine their relationship to
Rewaa Balaum, Leena Elbedour, Einav Alhozyel, Gal Meiri, Dikla Zigdon, Analya Michaelovski, Orly Kerub, Idan Menashe   +7 more
wiley   +1 more source

Precision and efficacy in congenital cataract surgery: a retrospective study of the 27-gauge vitrectomy system. [PDF]

Int Ophthalmol
Mancini M, Meduri A, Brancato C, Oliverio GW, De Luca L, Mancini A, Palino P, Aragona P, Pioppo A, Lo Giudice G.   +9 more
europepmc   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Associated congenital malformations, syndromes, and medical conditions in patients with orofacial clefts: a 10-year hospital-based study in Thailand. [PDF]

Front Oral Health
Sangharn K, Pisek P, Pisek A, Wangsrimongkol B, Pitiphat W, Bloch-Zupan A, Wichajarn K, Morkmued S.   +7 more
europepmc   +1 more source

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source

Global Burden of Pediatric Cardiovascular Diseases of Congenital and Non-Congenital Trends from 1992 to 2021. [PDF]

Commun Med (Lond)
Jing Z, Su Z, Liu Y, Wang H, Zou Z, Zhang H.   +5 more
europepmc   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source