Results 81 to 90 of about 794,449 (295)

Congenital segmental dilatation of the intestine in extremely low birth weight infants

Journal of Pediatric Surgery Case Reports, 2020
Congenital segmental dilatation of the intestine can arise from various etiologies. Herein, we describe two cases of congenital segmental dilatation of intestine in extremely low birth weight infants of different etiologies, namely muscular abnormalities
Yoichi Nakagawa, Tohru Harada, Yuji Kaneoka   +2 more
doaj   +1 more source

Congenital abnormalities in sheep

, 1965
More than 60 forms of abnormality have been found in lambs in Western Australia and in some flocks the proportion of particular abnormalities has been as high as 8 per cent, of lambs born. In this article Dr.
Dennis, Stanley M
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Forest plot of the association between maternal SNRIs exposure and risk of congenital cardiovascular abnormalities in offspring.

, 2023
Forest plot of the association between maternal SNRIs exposure and risk of congenital cardiovascular abnormalities in offspring.
Weiyi Huang (504650), Susan Ayres (17479239), Robin L. Page (17479236), Alva O. Ferdinand (11008476), Samiran Sinha (3224619), Theresa Morris (540096)   +5 more
core   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Congenital Anterior Urethrocutaneous Fistula

, 2009
Purpose: Congenital anterior urethrocutaneous fistula is a rare anomaly that may present in an isolated fashion or in association with other penile abnormalities, such as chordee or hypospadias.
陳世乾, CALDAMONE, ANTHONY A.; CHEN, SHYH-CHYAN; ELDER, JACK S.; RITCHEY, MICHAEL L.; DIAMOND, DAVID A.; KOYLE, MARTIN A.   +1 more
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Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Heavy metals and trace elements in maternal blood and prevalence of congenital limb abnormalities among newborns: the Japan Environment and Children’s Study

Environmental Health and Preventive Medicine
Background: Heavy metals such as lead (Pb) and cadmium (Cd) have been associated with adverse pregnancy and developmental outcomes, including congenital abnormalities.
Atsuko Ikeda, Megasari Marsela, Chihiro Miyashita, Takeshi Yamaguchi, Yasuaki Saijo, Yoshiya Ito, Hiroyoshi Iwata, Sachiko Itoh, Mariko Itoh, Keiko Yamazaki, Naomi Tamura, Sumitaka Kobayashi, Reiko Kishi, the Japan Environment and Children’s Study Group   +13 more
doaj   +1 more source

Qualitative Assessment of Surgical Repair of Three Types of Unilateral Cleft Lip

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To assess the effect of the three types of unilateral cleft lip (UCL) [cleft lip only, cleft lip and alveolus, and cleft lip alveolus and palate] on the outcome of the repair.
Adekunle M. Adetayo, Abdurazzak Olanrewaju Taiwo, Modupe Olusola Adetayo, Moses A. Akinola, Wasiu Lanre Adeyemo   +4 more
doaj  

Characterization of Visual Pathway Abnormalities in Infants with Congenital Zika Syndrome Using CT and MRI

, 2019
Congenital malformations related to Zika virus infection were first described in 2015 among infants born in the Pernambuco state of Brazil. The congenital Zika syndrome since has been further characterized to include microcephaly, ocular abnormalities ...
Amanda Henderson; Thierry A. G. M. Huisman; Avner Meoded; Adriano Hazin; Vanessa van der Linden; William May
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