Results 101 to 110 of about 54,890 (322)

Radon induced hyperplasia: effective adaptation reducing the local doses in the bronchial epithelium [PDF]

open access: yesarXiv, 2016
There is experimental and histological evidence that chronic irritation and cell death may cause hyperplasia in the exposed tissue. As the heterogeneous deposition of inhaled radon progeny results in high local doses at the peak of the bronchial bifurcations, it was proposed earlier that hyperplasia occurs in these deposition hot spots upon chronic ...
arxiv  

Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]

open access: yesarXiv, 2023
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv  

Prevalence and Incidence of Dementia in Patients With Non‐Overtly Functional Adrenal Tumours

open access: yesClinical Endocrinology, Volume 102, Issue 4, Page 371-379, April 2025.
ABSTRACT Objective To investigate the prevalence and incidence of dementia in patients with non‐overtly functional adrenal tumours (NOFATs). Design A national retrospective register‐based study was conducted on patients diagnosed with NOFAT and controls diagnosed between 2005 and 2019, in Sweden.
Hadis Mirzaei   +4 more
wiley   +1 more source

Mutations Of Pro30Leu And Val281Leu Of The Cyp21 Gene In Patients Diagnosed With Ambiguous Genitalia. [PDF]

open access: yes, 2002
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders of adrenal ...
Fuziah, M.Z.   +5 more
core  

Modelling oral adrenal cortisol support [PDF]

open access: yesarXiv, 2020
A simplified mathematical model of oral hydrocortisone delivery in adrenal insufficiency is described; the model is based on three components (gastric hydrocortisone, free serum cortisol and bound serum cortisol) and is formulated in terms of linear kinetics, taking into account the dynamics of glucocorticoid-protein binding.
arxiv  

Glucocorticoid activity of adrenal steroid precursors in untreated patients with congenital adrenal hyperplasia.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2019
CONTEXT AND OBJECTIVE We describe clinical features and biochemical characteristics of a unique population of severely affected untreated patients with congenital adrenal hyperplasia (CAH) from an Indonesian population, with proven cortisol deficiency ...
M. Engels   +8 more
semanticscholar   +1 more source

Establishing a liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) method for both 18‐hydroxycorticosterone and its interference: Revisiting the specificity characteristic of LC‐MS/MS in the steroid measurement

open access: yesInterdisciplinary Medicine, Volume 3, Issue 2, March 2025.
This study presents an innovative methodological approach for the identification and verification of the potential interference of 18‐hydrocorticosterone in human plasma using high‐performance liquid chromatography‐tandem time‐of‐flight mass spectrometry, demonstrating the critical importance of optimal chromatographic conditions and verification of ...
Songlin Yu   +3 more
wiley   +1 more source

Slipped capital femoral epiphysis in an adolescent with congenital adrenal hyperplasia: A case report

open access: yesClinical Case Reports
Key Clinical Message In previous reports, hypothyroidism, hypopituitrism, and hypogonadism were common endocrine causes of SCFE, but this is the first time that congenital adrenal hyperplasia has been observed.
Yi‐Fan Huang   +2 more
doaj   +1 more source

Case report: Coexistence of Jacobs syndrome, congenital adrenal hyperplasia, and ambiguous genitalia in a male infant

open access: yesClinical Case Reports, 2023
Key Clinical Message Jacobs syndrome and congenital adrenal hyperplasia are separate entities but share common clinical features such as ambiguous genitalia.
Qaisar Ali Khan   +9 more
doaj   +1 more source

Congenital anomalies from a physics perspective. The key role of "manufacturing" volatility [PDF]

open access: yes, 2019
Genetic and environmental factors are traditionally seen as the sole causes of congenital anomalies. In this paper we introduce a third possible cause, namely random "manufacturing" discrepancies with respect to ``design'' values. A clear way to demonstrate the existence of this component is to ``shut'' the two others and to see whether or not there is
arxiv   +1 more source

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