A case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic disorders [PDF]
Clinical Case Reports (discontinued), 2022 This is a case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic events. His fibrinogen concentration was negatively correlated with thrombin time and prothrombin time and abnormally negatively correlated with plasma D‐dimer levels ...
Dai Wei, Zhuohua Wu, Pingyi Xu
exaly +4 more sources
Diagnosing and Managing Paradoxical Deep Vein Thrombosis in a Patient With Congenital Afibrinogenemia [PDF]
eJHaemCongenital afibrinogenemia, classically a bleeding disorder, can paradoxically predispose to thrombosis, potentially due to disruptions in fibrin‐mediated thrombin clearance and plasmin activation.
Altamash Jawadi +9 more
doaj +3 more sources
Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management [PDF]
Diagnostics, 2021 Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative (dysfibrinogenemia and hypodysfibrinogenemia) disorders. The clinical phenotype is highly heterogeneous,
Tomáš Šimurda +2 more
exaly +4 more sources
Identification of novel mutations in congenital afibrinogenemia patients and molecular modeling of missense mutations in Pakistani population [PDF]
Thrombosis Journal, 2017 Background Congenital afibrinogenemia (OMIM #202400) is a rare coagulation disorder that was first described in 1920. It is transmitted as an autosomal recessive trait that is characterized by absent levels of fibrinogen (factor I) in plasma ...
Arshi Naz +9 more
doaj +2 more sources
Congenital Afibrinogenemia presenting as antenatal intracranial bleed: a case report [PDF]
Italian Journal of Pediatrics, 2010 Congenital afibrinogenemia is a very rare inherited coagulation disorder, characterized by virtual absence of plasma fibrinogen (factor I). There are only about 250 cases reported in the world literature 1.
Parapurath Rajiv +2 more
doaj +2 more sources
Congenital Afibrinogenemia [PDF]
Medicine, 2016 Afibrinogenemia is a rare coagulation disorder. Clinical features of spontaneous bleeding, bleeding after minor trauma, or after surgery have been described as well as thrombo-embolic complications. In this article, we presented the case of a 19-year old female with congenital afibrinogenemia who was admitted with a spontaneous intrahepatic hematoma ...
Malaquin, Stephanie +5 more
europepmc +4 more sources
Congenital afibrinogenemia in a newborn
Sanamed, 2022 Introduction: Congenital afibrinogenemia is a rare coagulation disorder characterized by a deficiency in the fibrinogen molecule. Fibrinogen is a hexameric glycoprotein consisting of a polypeptide chain encoded by FGB, FGA, and FGG and is required for ...
Özay Mustafa +2 more
doaj +3 more sources
Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death
Clinical and Applied Thrombosis/Hemostasis, 2020 Congenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia.
Yue Teng
exaly +2 more sources
Recurrent myocardial infarction in a case of congenital Afibrinogenemia
Heart Views, 2014 Afibrinogenemia is a rare autosomal recessive bleeding disorder with an estimated prevalence of 1:1,000,000. Usual presentation of this disorder is spontaneous bleeding, bleeding after minor trauma and excessive bleeding during interventional procedures.
Soumya Patra +4 more
doaj +2 more sources
Correction to "A Case of Congenital Afibrinogenemia With Multiple Thrombotic and Hemorrhagic Disorders". [PDF]
Clin Case RepClinical Case Reports, Volume 12, Issue 11, November 2024.
europepmc +2 more sources