Results 211 to 220 of about 8,625 (250)
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Congenital factor VII deficiency a case report
Blut Zeitschrift für die Gesamte Blutforschung, 1973A case of congenital factor VII deficiency is reported. The proposita is a 3-month old female infant who presented undue bleeding from the umbilical stump and several episodes of melena which promptly subsided after whole blood or plasma transfusions. The main coagulation features were: prolonged prothrombin time, normal Stypven-cephalin clotting time,
A, Girolami +3 more
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Clinical aspects of congenital factor VII deficiency
The American Journal of Medicine, 1964Abstract The reported cases of severe, isolated congenital factor VII deficiency are reviewed and compared with the present studies. In all, fifty-two cases fulfill the necessary diagnostic criteria. The deficiency appears to be due to a "defective" autosomal gene, full clinical expression of hemorrhagic symptoms appearing only in the homozygous ...
V J, MARDER, N R, SHULMAN
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Arthropathy and surgery in congenital factor VII deficiency
The American Journal of Medicine, 1988A 35-year-old woman with severe (less than 1 percent) factor VII deficiency had recurrent hemarthroses involving the left knee, leading to deformity, pain, and virtually complete loss of function. It was elected to perform a total knee replacement. In preparation for surgery, the patient received heat-treated prothrombin complex concentrate containing ...
T, Kuzel +3 more
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Surgery for Scoliosis in Congenital Factor VII Deficiency
Archives of Pediatrics & Adolescent Medicine, 1982A patient with severe congenital factor VII deficiency had an anterior and posterior spine fusion for severe scoliosis. For both operations, hemostatic management was 50 units of prothrombin complex concentrate (Konyne) per kilogram of body weight before surgery and every eight hours after surgery for the first 24 hours. Subsequently, 10 mL/kg of fresh
W B, Greene, C W, McMillan
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Intracranial hemorrhage in congenital factor VII deficiency
The Journal of Pediatrics, 1979However, to our knowledge, this has not been previously associated with cavernous sinus thrombosis. The majority of the sequelae of cavernous sinus thrombosis are due to cranial nerve damage with resultant ophthalmoplegia. In addition, ischemic changes secondary to carotid arteritis may result in blindness, hemiplegia, or hypopituitarism.
K K, Matthay, M A, Koerper, A R, Ablin
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Congenital Combined Factor VII and Factor VIII Deficiency
Acta Haematologica, 2009This paper describes two family members who have a combined hereditary deficiency of factors VII and VIII. The propositus, a 16-year-old male, presented with recurrent gastrointestinal bleeding. He and his mother had moderate defects of factors VII and VIII. The propositus received factor VIII cover, during and after a laparatomy.
S J, Machin, B R, Miller
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Congenital Hypoproconvertinemia (Factor VII Deficiency)
Acta Haematologica, 2009Two new cases of congenital factor VII deficiency are reported. They are two 7-year-old boys belonging to two different kindreds. The main clinical features were: bleeding from the gums, epitaxis (one patient), easy bruising, melena, posttraumatic and spontaneous hemarthrosis.
A. Girolami +4 more
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Use of Recombinant, Activated Factor VII in the Treatment of Congenital Factor VII Deficiencies
Vox Sanguinis, 1999Abstract Background and Objectives: Factor VII (FVII) deficiency is a rare coagulation disorder, historically treated with prothrombin complex concentrates or plasma‐derived FVII concentrates. We treated such patients (n=17) with a recombinant, activated FVII preparation.
G, Mariani +4 more
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Recombinant Factor VIIa for the Treatment of Congenital Factor VII Deficiency
Seminars in Thrombosis and Hemostasis, 2000Factor VII deficiency is a rare autosomal bleeding disorder with a highly variable hemorrhagic predisposition. Severe bleeding, including hemarthroses, may be encountered when plasma factor VII levels are below 1%. Patients have prolonged prothrombin times, and the final diagnosis is established by quantitative factor VII assays.
M, Hunault, K A, Bauer
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Clinical picture and management of congenital factor VII deficiency
Haemophilia, 2004Summary. In patients with congenital FVII deficiency, bleeding manifestations and clinical presentation vary widely, ranging from asymptomatic subjects to patients with haemorrhages that may cause important handicaps. Owing to menorrhagia, which occurs in about two‐thirds of women of fertile age, bleeding is more frequent in women than in men.
MARIANI G +3 more
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