Results 31 to 40 of about 99,772 (304)

Interventional Partial Cavopulmonary Connection: Initial Clinical Experience With Acute Procedural up to Midterm Results

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Creation of a partial cavopulmonary anasthomosis in patients with isolated right‐sided heart failure or patients with cyanosis and intracardial right‐to‐left shunt and reduced blood flow in the pulmonary circulation may provide a significant ...
Katarzyna Gendera, Peter Ewert, Stanimir Georgiev, Andreas Eicken, Daniel Tanase, Kristina Borgmann, Paul Philipp Heinisch, Nicole Nagdyman, Julie Cleuziou, Dunja Renner, Pinar Bambul Heck   +10 more
doaj   +1 more source

Assessment of anatomy of the aorta in patients with a coarctation of aorta

The Cardiothoracic Surgeon, 2023
Background Coarctation of the aorta (CoA) is a congenital heart disease characterized by the narrowing of the aorta, resulting in reduced blood flow to the body and increased pressure in the left ventricle.
B. B. Turaev, Kh. K. Abralov, B. Kh. Kobiljonov, N. Sh. Ibragimov   +3 more
doaj   +1 more source

Nationwide Survey Reveals High Prevalence of Non-Swimmers among Children with Congenital Heart Defects

Children, 2023
Background: Physical activity is important for children with congenital heart defects (CHD), not only for somatic health, but also for neurologic, emotional, and psychosocial development. Swimming is a popular endurance sport which is in general suitable
Christian Apitz, Dominik Tobias, Paul Helm, Ulrike M. Bauer, Claudia Niessner, Jannos Siaplaouras   +5 more
doaj   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

CardioCel® For Repair of Congenital Heart Defects – Nationwide Results of Over 1000 Implants

, 2023
OBJECTIVES: To assess the mid-term performance of CardioCel for the repair of congenital heart defects. METHODS: Data were retrospectively collected from databases and hospital records in 3 congenital cardiac surgery centres in Australia.
Betts, Kim S., Patukale, Aditya A, Alphonso, Nelson, Kim S Betts, Karl, Tom R., Betts, Kim S, Jessica Suna, Karl, Tom R, Patukale, Aditya A., Nelson Alphonso, David Andrews, Prem Venugopal, Marathe, Supreet P., Supreet P Marathe, Brizard, Christian, Christian Brizard, Aditya A Patukale, https://orcid.org/, Anand, Abhishek, Marathe, Supreet P, Venugopal, Prem, Shetty, Gautham, Tom R Karl, Michael Daley, Abhishek Anand, Andrews, David, Daley, Michael, Suna, Jessica, Gautham Shetty   +28 more
core   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Spatio-Temporal Distribution and Demographic Characteristics of Congenital Heart Defects in Guangdong, China, 2016–2020

Frontiers in Public Health, 2022
BackgroundCongenital heart defects are the most common type of birth defects and bring a heavy disease burden in China. Examining the temporal and spatial trends of congenital heart defects epidemics can give some elementary knowledge for succeeding ...
Huazhang Miao, Huazhang Miao, Huazhang Miao, Qinghui Zeng, Zengping Shi, Yi Xia, Lushaobo Shi, Dongxue Chen, Pi Guo, Yingxian Zhu, Dong Wang   +10 more
doaj   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

It Is Not Carved in Stone—The Need for a Genetic Reevaluation of Variants in Pediatric Cardiomyopathies

Journal of Cardiovascular Development and Disease, 2022
(1) Background: In cardiomyopathies, identification of genetic variants is important for the correct diagnosis and impacts family cascade screening. A classification system was published by the American College of Medical Genetics and Genomics (ACMG) in ...
Dominik Sebastian Westphal, Kathrin Pollmann, Christoph Marschall, Annette Wacker-Gussmann, Renate Oberhoffer-Fritz, Karl-Ludwig Laugwitz, Peter Ewert, Cordula Maria Wolf   +7 more
doaj   +1 more source