Results 91 to 100 of about 24,959 (186)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Dysregulation of the Scribble/YAP/β-catenin axis sustains the fibroinflammatory response in a PKHD1^-/- mouse model of congenital hepatic fibrosis. [PDF]

FASEB J, 2022
Fabris L, Milani C, Fiorotto R, Mariotti V, Kaffe E, Seller B, Sonzogni A, Strazzabosco M, Cadamuro M.   +8 more
europepmc   +1 more source

PSC‐DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease‐specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertainty can delay appropriate
Miki Scaravaglio, Rodrigo V. Motta, Laura Cristoferi, Cesare Maino, Alberto Marini, Eugenia Nofit, Eugenia Pesatori, Camilla Gallo, Francesca Bolis, Daphne D'Amato, Armando Curto, Federica Malinverno, Alessio Gerussi, Raffaella Viganò, Mauro Viganò, Stephen J. Rossi, Kris V. Kowdley, Pietro Invernizzi, Alessandra Nardi, Marco Carbone, Emma L. Culver   +20 more
wiley   +1 more source

Pediatric Ciliopathy Linked to TULP3 Variant—A Case Report

Journal of Molecular Pathology
Ciliopathies, initially known as fibrocystic liver diseases, encompass a group of inherited disorders characterized by cystic dilatation of intrahepatic bile ducts and portal fibrosis, frequently associated with renal anomalies.
Mrunmayi Prashant Marathe, Snehavardhan Pandey, Anusha Kulkarni, Thenral S. Geetha, Ashish Bavdekar   +4 more
doaj   +1 more source

Congenital hepatic fibrosis in a young boy with congenital hypothyroidism: A case report. [PDF]

World J Clin Cases, 2021
Xiao FF, Wang YZ, Dong F, Li XL, Zhang T.   +4 more
europepmc   +1 more source

Analysis of the Mediating Role of Cytokines in the Relationship Between Nonalcoholic Fatty Liver Disease and Cognitive Impairment After Ischemic Stroke

Brain and Behavior, Volume 16, Issue 10, October 2026.
This article reveals the mediating role of cytokine levels between non‐alcoholic fatty liver disease and post‐stroke cognitive impairment, providing new therapeutic targets for post‐stroke cognitive dysfunction. Abstract Objective To explore whether nonalcoholic fatty liver disease (NAFLD) is associated with poststroke cognitive impairment (PSCI) and ...
Xin Du, Jingwei Li
wiley   +1 more source

A discarded synonymous variant in NPHP3 explains nephronophthisis and congenital hepatic fibrosis in several families. [PDF]

Hum Mutat, 2021
Olinger E, Alawi IA, Al Riyami MS, Salmi IA, Molinari E, Faqeih EA, Al-Hamed MH, Barroso-Gil M, Powell L, Al-Hussaini AA, Rahim KA, Almontashiri NAM, Miles C, Shril S, Hildebrandt F, Consortium GER, Wilson IJ, Sayer JA.   +17 more
europepmc   +1 more source

Expression of COL6A1 in Tumor Matrix of Cholangiocarcinoma and Its Mechanism of Tumor Progression

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Cholangiocarcinoma (CCA), a malignant tumor originating from the bile duct epithelial cells, is characterized by aggressive invasion and poor prognosis. Abnormal remodeling of the tumor microenvironment plays a pivotal role in its disease progression.
Weibin Zhang, Chongshi Gao, Chongzhou Lan, Jia Dong, Boxing Xu, Yingmei Li, Jin Dai, Baitong Che, Cheng Li, Gang Dong, Yunfei Wu, Bo Li, Cheng Yang, Lingmei Kong   +13 more
wiley   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Parenteral nutrition and hospital outcomes in Australian adults: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 7, Page 1003-1013, October 2026.
Abstract Background There is limited information regarding real‐world use of parenteral nutrition in hospitals. The objective of the study was to provide a real‐world description of parenteral nutrition administration in hospitalized patients. Methods This was a descriptive cohort study in 507 hospitalized adults who received parenteral nutrition at ...
Frank M. P. van Haren, Sumeet Rai, Andrew Thomson, Josie Russell‐Brown, Mary Nourse, Shakira Spiller, Louise Herlihy, Sean Weng Chan, Peter Velloza, Matthew H. Anstey, Robert N. Palmer, Bianca Mammana, Tania Elderkin, Adam Visser, Matt Brain, Sarah Mineall, Emma J. Ridley   +16 more
wiley   +1 more source