Results 101 to 110 of about 24,959 (186)
Organoids: Current Applications and Future Directions
MedComm, Volume 7, Issue 10, October 2026.Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng +14 more
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Multiple hepatocyte nuclear factor 1A (HNF1A)-inactivated hepatocellular adenomas arising in a background of congenital hepatic fibrosis. [PDF]
J Pathol Transl Med, 2021 Lee Y +5 more
europepmc +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.A 24‐year‐old heterozygous woman presented with lifelong hypotonia and slowly progressive, asymmetric axial and limb‐girdle weakness with facial/ocular involvement and restrictive ventilatory impairment (FVC 53.12% predicted). Multimodal evaluation (EMG, muscle MRI, and whole‐exome sequencing [WES]) identified a de novo MTM1 frameshift variant ...
Lijun Chen, Yingxiao Bao, Gonglu Liu
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1083-1096, October 2026.In the POISE open‐label extension, patients with primary biliary cholangitis with inadequate response or intolerance to ursodeoxycholic acid received long‐term obeticholic acid (OCA) treatment. Findings demonstrated a safety profile consistent with the known characteristics of OCA, with no unexpected safety signals, while supporting sustained efficacy ...
Christopher L. Bowlus +8 more
wiley +1 more source
[A case of congenital hepatic fibrosis diagnosed and treated by transjugular intrahepatic portosystemic shunt]. [PDF]
Zhonghua Gan Zang Bing Za Zhi, 2021 Wang J +6 more
europepmc +1 more source
The Clinical Respiratory Journal, Volume 20, Issue 10, October 2026.This study investigated serum levels of cold‐inducible RNA‐binding protein (CIRP) and C‐X‐C motif chemokine ligand 5 (CXCL5) in 485 children with Mycoplasma pneumoniae pneumonia. Elevated levels of both biomarkers were independently associated with poor prognosis and positively correlated with neutrophil extracellular trap markers, suggesting their ...
Litao Wan +7 more
wiley +1 more source