Results 71 to 80 of about 265,208 (194)

Diagnosis and management of congenital hypopituitarism in children

Archives de Pédiatrie
Hypopituitarism (or pituitary deficiency) is a rare disease with an estimated prevalence of between 1/16,000 and 1/26,000 individuals, defined by insufficient production of one or several anterior pituitary hormones (growth hormone [GH], thyroid-stimulating hormone [TSH], adrenocorticotropic hormone [ACTH], luteinizing hormone [LH], follicle ...
Castets, Sarah, Vergier, Julia, Reynaud, Rachel, Thomas-Teinturier, Cécile, Villanueva, Carine, Amsellem, Jessica, Coutant, Régis, Barat, Pascal, Brun, Gilles, Quoc, Emmanuel Bui, Carel, Jean Claude, de Filippo, Gian Paolo, Kipnis, Clara, Martinerie, Laetitia, Léger, Juliane, Saveanu, Alexandru, Teissier, Natacha   +16 more
openaire   +3 more sources

Hypopituitarism in Childhood

, 2002
Background Childhood hypopituitarism may be present at birth or may be acquired. Early diagnosis and treatment promote the best possible outcomes.
Mitchell E. Geffner
core   +1 more source

Hypopituitarism in Patients with Blepharophimosis and FOXL2 Mutations

, 2020
International audienceBackground: FOXL2 is the gene involved in blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). There have been few single case reports of growth hormone deficiency (GHD) with this syndrome, and Foxl2 is known to be ...
Roucher-Boulez, Florence, Chabre, Olivier, Saveanu, Alexandru, Morel, Yves, Amati-Bonneau, Patrizia, Bonneau, Dominique, Nicolino, Marc, Brue, Thierry, Girardin, Celine, Villanueva, Carine, Reynaud, Rachel, Castets, Sarah, Mallet, Delphine, Mallet-Motak D, Girardin C, Castets S, Saveanu A, Morel Y, Nicolino M, Bonneau D, Villanueva C, Chabre O, Amati-Bonneau P, Brue T, Reynaud R, Roucher-Boulez F   +25 more
core   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

A heterozygous microdeletion of 20p12.2-3 encompassing PROKR2 and BMP2 in a patient with congenital hypopituitarism and growth hormone deficiency

, 2017
Congenital growth hormone deficiency is a rare disorder with an incidence of approximately 1 in 4,000 live births. Pituitary development is under the control of a multitude of spatiotemporally regulated signaling molecules and transcription factors ...
Wright, Neville B, Murray, Phillip G, Skae, Mars S, Parsons, Samuel J H, Emma Burkitt-Wright, Mars S. Skae, Phillip G. Murray, Neville B. Wright, Burkitt-Wright, Emma, Samuel J. H. Parsons   +9 more
core   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, Volume 105, Issue 1, Page 14-21, July 2026.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

Fertility induction associated with improved peripheral reproductive parameters in male Prop1df/dfmice subjected to GH and levothyroxine replacement [PDF]

Archives of Endocrinology and Metabolism
Objective: The aim of this study was to characterize the parameters of reproductive anatomy and pituitary hormone expression levels in ames dwarf mice (Prop1df/df).
Bruna Viscardi Azevedo, Juliana Moreira Marques, Nicholas Trigueiro, Victor Yuji Yariwake, Mariana Matera Veras, Leticia Kaory Tamashiro, Robison Cruz, Luciani R. Silveira de Carvalho   +7 more
doaj   +1 more source

Agenesis of internal carotid artery and hypopituitarism: case report and review of literature.

, 2012
Context: Agenesis of the internal carotid artery and hypoplasia of the internal carotid artery are rare congenital abnormalities, involving less than 0.01% of the general population.
Strocchio L, Introzzi F, Incorpora G, Merli P, Zuffardi O, Savasta S, Della Mina E, Lanati G, Simoncelli A, Larizza D   +9 more
core   +2 more sources

Genetic causes of hypopituitarism

Archives of Medical Science, 2019
Hypopituitarism in neonates is rare, but has life-threatening complications if untreated. This review describes the features of hypopituitarism and the evidence for which infants in whom a genetic cause should be suspected.
Katherine Parkin, Ritika Kapoor, Ravindra Bhat, Anne Greenough   +3 more
doaj   +1 more source

Combined pituitary hormone deficiency harboring CHD7 gene missense mutation without CHARGE syndrome: a case report

BMC Endocrine Disorders, 2023
Background Heterozygous loss-of-function mutations in the chromodomain helicase DNA-binding protein 7 (CHD7) gene cause CHARGE syndrome characterized by various congenital anomalies.
Yoshinari Obata, Kana Takayama, Hideyuki Nishikubo, Aoki Tobimatsu, Izumi Matsuda, Yuhei Uehara, Yumiko Maruo, Hiroyuki Sho, Motohiro Kosugi, Tetsuyuki Yasuda   +9 more
doaj   +1 more source