Results 1 to 10 of about 416,939 (310)

Status of temozolomide use without insurance coverage in patients with aggressive pituitary neuroendocrine tumors

open access: yesEndocrine Journal
The 2017 World Health Organization classification described aggressive pituitary neuroendocrine tumor (PitNET) as “a tumor with strong invasiveness and rapid growth, which is difficult to treat with surgery, radiation therapy, or drug therapy,” which ...
Atsushi Ishida   +8 more
doaj   +1 more source

Cholesterol-activated stress granules reduce the membrane localization of DRD2 and promote prolactinoma dopamine agonists resistance

open access: yesActa Neuropathologica Communications
Prolactinoma is the most prevalent pituitary neuroendocrine tumor and dopamine agonists (DAs) targeting dopamine D2 receptor (DRD2) are recommended as the first-line treatment. However, varying degrees of DA resistance limit patient benefit.
Yuyang Peng   +8 more
doaj   +1 more source

The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease

open access: yesJournal of Translational Medicine
Background Cushing’s disease (CD) is a clinical syndrome caused by excessive secretion of adrenocorticotropic hormone (ACTH) from a pituitary corticotroph adenoma, resulting in adrenal cortical hyperplasia and overproduction of cortisol.
Fang Liu   +9 more
doaj   +1 more source

Pituitary apoplexy induced by gonadotropin-releasing hormone agonist administration: a rare complication of prostate cancer treatment

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2020
Gonadotropin-releasing hormone (GnRH) agonists, currently used in the treatment of advanced prostate cancer, have been described as a rare cause of pituitary apoplexy, a potentially life-threatening clinical condition. We report the case of a 69-year-old
Mariana Barbosa   +4 more
doaj   +1 more source

Fully endoscopic far-lateral supracerebellar infratentorial approach for trigeminal neuralgia: illustrative case reports

open access: yesChinese Neurosurgical Journal
Background Trigeminal neuralgia (TN) is a common cause of craniofacial pain. The retrosigmoid approach is usually used to treat TN, but no cases of endoscopic far-lateral supracerebellar infratentorial approach (EF-SCITA) were used to undergo operation ...
Hong Yao   +5 more
doaj   +1 more source

Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma

open access: yesScientific Reports, 2017
Lactate dehydrogenase A (LDHA) has been reported to be involved in the initiation and progression of tumors. However, the potential role of LDHA in pituitary adenoma (PA) remains unknown.
Jiayin An   +9 more
doaj   +1 more source

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

open access: yesInternational Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis   +4 more
doaj   +1 more source

Perioperative management of endoscopic transsphenoidal pituitary surgery

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2020
The contemporary embrace of endoscopic technology in the approach to the anterior skull base has altered the perioperative landscape for patients requiring pituitary surgery.
Martin Hanson   +5 more
doaj   +1 more source

Identifying Facial Features and Predicting Patients of Acromegaly Using Three-Dimensional Imaging Techniques and Machine Learning

open access: yesFrontiers in Endocrinology, 2020
Objective: Facial changes are common among nearly all acromegalic patients. As they develop slowly, patients often fail to notice such changes before they become obvious. Consequently, diagnosis and treatment are often delayed.
Tian Meng   +21 more
doaj   +1 more source

Long-term quality of life in adult craniopharyngioma patients: correlation with pituitary stalk section after endoscopic endonasal surgery

open access: yesActa Neurochirurgica
Purpose Craniopharyngiomas are benign but locally aggressive tumors whose surgical treatment poses a challenge due to their proximity to critical structures. While gross total resection (GTR) may reduce recurrence risk, it often leads to significant long-
Irene Portonero   +9 more
doaj   +1 more source

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