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The 2017 World Health Organization classification described aggressive pituitary neuroendocrine tumor (PitNET) as “a tumor with strong invasiveness and rapid growth, which is difficult to treat with surgery, radiation therapy, or drug therapy,” which ...
Atsushi Ishida +8 more
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Prolactinoma is the most prevalent pituitary neuroendocrine tumor and dopamine agonists (DAs) targeting dopamine D2 receptor (DRD2) are recommended as the first-line treatment. However, varying degrees of DA resistance limit patient benefit.
Yuyang Peng +8 more
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The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease
Background Cushing’s disease (CD) is a clinical syndrome caused by excessive secretion of adrenocorticotropic hormone (ACTH) from a pituitary corticotroph adenoma, resulting in adrenal cortical hyperplasia and overproduction of cortisol.
Fang Liu +9 more
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Gonadotropin-releasing hormone (GnRH) agonists, currently used in the treatment of advanced prostate cancer, have been described as a rare cause of pituitary apoplexy, a potentially life-threatening clinical condition. We report the case of a 69-year-old
Mariana Barbosa +4 more
doaj +1 more source
Background Trigeminal neuralgia (TN) is a common cause of craniofacial pain. The retrosigmoid approach is usually used to treat TN, but no cases of endoscopic far-lateral supracerebellar infratentorial approach (EF-SCITA) were used to undergo operation ...
Hong Yao +5 more
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Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma
Lactate dehydrogenase A (LDHA) has been reported to be involved in the initiation and progression of tumors. However, the potential role of LDHA in pituitary adenoma (PA) remains unknown.
Jiayin An +9 more
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Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis +4 more
doaj +1 more source
Perioperative management of endoscopic transsphenoidal pituitary surgery
The contemporary embrace of endoscopic technology in the approach to the anterior skull base has altered the perioperative landscape for patients requiring pituitary surgery.
Martin Hanson +5 more
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Objective: Facial changes are common among nearly all acromegalic patients. As they develop slowly, patients often fail to notice such changes before they become obvious. Consequently, diagnosis and treatment are often delayed.
Tian Meng +21 more
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Purpose Craniopharyngiomas are benign but locally aggressive tumors whose surgical treatment poses a challenge due to their proximity to critical structures. While gross total resection (GTR) may reduce recurrence risk, it often leads to significant long-
Irene Portonero +9 more
doaj +1 more source

