Results 101 to 110 of about 630,874 (291)

Maternal thyroid function and child educational attainment: prospective cohort study [PDF]

, 2018
Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline, Lawlor, Debbie A., Lindsay, Robert S., McConnachie, Alex, Nelson, Scott M., Ring, Susan M., Sattar, Naveed, Smith, George D.   +7 more
core   +3 more sources

The Impact of Disease Activity and Medications on Pregnancy and Fetal Outcomes in Women With Inflammatory Bowel Disease: A Cohort Study From the IBD‐ME Group

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Women with inflammatory bowel disease (IBD) and their children are at higher risk of adverse outcomes. The primary aim was to examine the association between IBD and adverse pregnancy outcomes. The secondary aim was to assess the impact of maternal IBD and medications used on children's outcomes.
Mahmoud Mosli, Nahla Azzam, Majid Almadi, Heba Alfarhan, Mansour Altuwaijiri, Abdulrahman Aljebreen, Othman Alharbi, Mohammed Abaalkhail, Maryam Jaran, Abdulaziz Altamimi, Nouf Al Turki, Lubna Alharbi, Joud A. L. Ghamdi, Amal Al Dakhil   +13 more
wiley   +1 more source

Molecular spectrum of TSHβ subunit gene defects in central hypothyroidism in the UK and Ireland. [PDF]

, 2016
OBJECTIVE: Homozygous mutations in the TSH beta subunit gene (TSHB) result in severe, isolated, central congenital hypothyroidism (CCH). This entity evades diagnosis in TSH-based congenital hypothyroidism (CH) screening programmes in the UK and Ireland ...
Bernhard, B, Chatterjee, VK, Crowne, E, Dattani, MT, Jaleel, S, Kirk, J, Lyons, G, Nicholas, AK, Roche, EF, Schoenmakers, E, Schoenmakers, N   +10 more
core   +2 more sources

Case reports of oral appliance therapy on three young adults with Down syndrome and OSA

Journal of Prosthodontics, EarlyView.
Abstract Patients with Down syndrome (DS) have a high incidence of obstructive sleep apnea (OSA) due to hypotonia, weight, underdeveloped midface, and relative macroglossia. This article presents three cases of young adults with DS, who were diagnosed with mild to severe OSA and unable to tolerate positive airway pressure therapy.
Jingjing Zhang, Yuuya Kohzuka, Kathleen M. Bennett, Fernanda R. Almeida   +3 more
wiley   +1 more source

The Iowa Perinatal Letter, April-May-June 2008, Vol. 29, no. 2 [PDF]

, 2008
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Intelligence Quotient at the Age of Six years of Iranian Children with Congenital Hypothyroidism

Indian Pediatrics, 2018
ObjectiveTo evaluate the success rate of the National newborn screening program in maintenance of intelligent quotient (IQ) of children with congenital hypothyroidism in Iran.DesignRetrospective cohort study.MethodsThe IQ scores, in three subsets of ...
K. Rahmani, S. Yarahmadi, K. Etemad, Y. Mehrabi, Nasrin Aghang, A. Koosha, H. Soori   +6 more
semanticscholar   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Hipotireoidismo neonatal transitório em um menino com translocação não balanceada t(8;16) [PDF]

, 2012
Defeitos genéticos resultando em deficiência hormonal tireoidiana podem ser encontrados em cerca de 10% dos pacientes com hipotireoidismo congênito permanente, porém a identificação de anormalidades genéticas associadas à forma transitória da doença é ...
Araújo, Juliana Forte Mazzeu de, Córdoba, Mara Santos, Ferrari, Íris, Neves, Francisco de Assis Rocha, Ramos, Helton Estrela, Secchi, Luciana Antunes de Almeida   +5 more
core   +1 more source

Sucessful Transition in Rare Endocrine Diseases: Patient Experiences in a French Reference Centre

Clinical Endocrinology, Volume 103, Issue 6, Page 833-840, December 2025.
ABSTRACT Objective This study aimed to evaluate the experiences of patients who had a joint endocrinology consultation for transition to adult care at Marseille university hospitals between 2010 and 2020, focusing on patient follow‐up, satisfaction, difficulties, and expectations.
Karine Aouchiche, Thierry Brue, Emeline Marquant, Gilbert Simonin, Sarah Castets, Rachel Reynaud, Frederique Albarel   +6 more
wiley   +1 more source

Unbalanced long-chain fatty acid beta-oxidation in newborns with cystic fibrosis and congenital hypothyroidism

Molecular Genetics and Metabolism Reports
Background: Immediately after birth, adaptation to the extrauterine environment includes an upregulation of fatty acid catabolism. Cystic fibrosis and untreated hypothyroidism exert a life-long impact on fatty acid metabolism, but their influence during ...
Catherina T. Pinnaro, Kelli K. Ryckman, Aliye Uc, Andrew W. Norris   +3 more
doaj   +1 more source