Results 41 to 50 of about 302,141 (331)

Human Placental Trophoblasts Are Resistant to Trypanosoma cruzi Infection in a 3D-Culture Model of the Maternal-Fetal Interface

Frontiers in Microbiology, 2021
Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas Disease (CD), is transmitted to humans by infected kissing bugs, blood transfusion, organ transplantation, and from mother-to-child.
Erica Silberstein, Kwang Sik Kim, David Acosta, Alain Debrabant   +3 more
doaj   +1 more source

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]

, 2018
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M, Castro, Eumenia CC, Chiu, Charles Y, Giavedoni, Luis, Hodara, Vida L, Layne-Colon, Donna, Li, Tony, Martyn, Calla, Parodi, Laura M, Patterson, Jean L, Reyes, Kevin, Rutherford, Julienne, Seferovic, Maxim, Suter, Melissa A, Sánchez-San Martín, Claudia, Tamhankar, Manasi, Tardif, Suzette D, Yagi, Shigeo   +17 more
core   +2 more sources

OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines

Journal of Immunology Research, 2019
Routine vaccination is among the most effective clinical interventions to prevent diseases as it is estimated to save over 3 million lives every year. However, the full potential of global immunization programs is not realised because population coverage
Nicola Cotugno, Alessandra Ruggiero, Veronica Santilli, Emma Concetta Manno, Salvatore Rocca, Sonia Zicari, Donato Amodio, Manuela Colucci, Paolo Rossi, Ofer Levy, Federico Martinon-Torres, Andrew J. Pollard, Paolo Palma   +12 more
doaj   +1 more source

Human Cytomegalovirus: detection of congenital and perinatal infection in Argentina [PDF]

, 2004
BACKGROUND: Human cytomegalovirus (CMV) is one of the most commonly found agents of congenital infections. Primary maternal infection is associated with risk of symptomatic congenital diseases, and high morbidity is frequently associated with very low ...
Alicia Alonso, Angélica Lidia Distéfano, B Zweygberg Wirgart, D Shibata, DJ Morris, E Gonczol, Fabián Martin, Fabián Pardon, GJ Demmler, J Darlington, JC Mendez, JR Murph, KB Fowler, M Barbi, M Barbi, M Brytting, M Shibata, MG Revello, MG Revello, NM Jiwa, PD Griffiths, PV Coyle, RJ Whitley, S Chou, SA Plotkin, SB Boppana   +25 more
core   +3 more sources

Low incidence of toxoplasma infection during pregnancy and in newborns in Sweden [PDF]

, 2001
To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978 children born in two regions in Sweden was determined.
Engman, ML, Evengard, B, Forsgren, M, Gilbert, R, Ivarsson, SA, Malm, G, Petersson, K, Tear-Fahnehjelm, K, Wiklund, S   +8 more
core   +2 more sources

Retrospective immunohistochemical analysis of human cytomegalovirus infection in the placenta and its association with fetal growth restriction

Fujita Medical Journal, 2023
Objectives: Fetal human cytomegalovirus (HCMV) infection might be involved in fetal growth restriction (FGR). Maternal serostatus and the prevalence of congenital HCMV infection are affected by various factors, such as socioeconomic status and ethnicity.
Yusuke Funato, Yuki Higashimoto, Yoshiki Kawamura, Yoshiko Sakabe, Minori Iwakura, Masaru Ihira, Kazuya Shiogama, Masafumi Miyata, Haruki Nishizawa, Takao Sekiya, Takuma Fujii, Isao Kosugi, Tetsushi Yoshikawa   +12 more
doaj   +1 more source

Cytomegalovirus and Epstein–Barr Virus Associations with Neurological Diseases and the Need for Vaccine Development

Vaccines, 2020
Herpesviruses have been isolated from a wide range of hosts including humans—for which, nine species have been designated. The human herpesviruses are highly host adapted and possess the capacity for latency, allowing them to survive in the host ...
Peter A. C. Maple
doaj   +1 more source

Evidence for high levels of vertical transmission in Toxoplasma gondii [PDF]

, 2009
Toxoplasma gondii is a highly ubiquitous and prevalent parasite. Despite the cat being the only definitive host, it is found in almost all geographical areas and warm blooded animals. Three routes of transmission are recognised: ingestion of oocysts shed
Buxton, D. THOMASSON, Dubey, E. A. WRIGHT, E. K. MORLEY, G. HIDE, Hide, J. E. SMITH, J. M. HUGHES, K. H. ELMAHAISHI, M. S. ELMAHAISHI, O. GERWASH, R. G. MURPHY, R. H. WILLIAMS, Rodger   +14 more
core   +1 more source

Congenital Cytomegalovirus Infection: A Narrative Review of the Issues in Screening and Management From a Panel of European Experts. [PDF]

, 2020
Maternal primary and non-primary cytomegalovirus (CMV) infection during pregnancy can result in in utero transmission to the developing fetus. Congenital CMV (cCMV) can result in significant morbidity, mortality or long-term sequelae, including ...
Blázquez-Gamero, D, Delforge, M-L, Foulon, I, Lazzarotto, T, Leruez-Ville, M, Luck, S, Modrow, S   +6 more
core   +1 more source

Congenital cytomegalovirus infection

Annals of the New York Academy of Sciences, 2010
Congenital cytomegalovirus (CMV) infection is a serious health problem. The obstacles for limiting this infection are the lack of public awareness on this issue, especially owing to the asymptomatic nature of CMV infections, the inefficacy of therapy, and the unsuccessful vaccine trials to date. It is therefore important to organize the current data to
Nicoletta Iacovidou, Z. Christoni, V. Papaevangelou, S. Kloudas, Angeliki Syggelou   +4 more
openaire   +6 more sources